Changes in lung function from baseline in trough and wm (0–4 h) FEV1 (l)
| Trough FEV1 (l) | |||||||||
| Day 2 | Day 15 | Day 28 | |||||||
| Placebo | FF/VI | Tx Diff (95% CI) | Placebo | FF/VI | Tx Diff (95% CI) | Placebo | FF/VI | Tx Diff (95% CI) | |
| LS mean change from baseline (SE) | 0.122 (0.0323) | 0.276 (0.0229) | 0.154 (0.075 to 0.234) | 0.113 (0.0387) | 0.285 (0.0253) | 0.172 (0.079 to 0.265) | 0.088 (0.0398) | 0.271 (0.0262) | 0.183 (0.087 to 0.279) |
| wm (0–4 h) FEV1 (l) | ||||||
| Day 1 | Day 28 | |||||
| Placebo | FF/VI | Tx Diff (95% CI) | Placebo | FF/VI | Tx Diff (95% CI) | |
| LS mean change from baseline (SE) | 0.022 (0.0259) | 0.222 (0.0182) | 0.201 (0.137 to 0.264) | 0.047 (0.0341) | 0.283 (0.0227) | 0.236 (0.154 to 0.319) |
FEV1, forced expiratory volume in one second; FF, fluticasone furoate; LS, least squares; Tx, treatment; VI, vilanterol, wm, weighted mean.