Table 2

Association of biomarkers risk score (BRS) and risk of type 2 diabetes and impaired fasting glucose (IFG)

Quintiles of BRSContinuous BRS
VariablesQ1Q2Q3Q4Q5OR (95% CI)p Value
N637642629648633
Median (range)2.3 (0.0 to 3.5)4.4 (3.6 to 5.2)6.0 (5.2 to 6.7)7.5 (6.8 to 8.5)9.7 (8.5 to 12.0)
Risk of type 2 diabetes
 Model 1*1.01.45 (0.88 to 2.40)3.29 (2.10 to 5.15)4.19 (2.70 to 6.52)6.45 (4.18 to 9.97)1.27 (1.22 to 1.33)<0.001
 Model 21.01.51 (0.91 to 2.50)3.28 (2.08 to 5.18)4.35 (2.77 to 6.81)6.72 (4.32 to 10.45)1.28 (1.22 to 1.34)<0.001
 Model 31.01.51 (0.91 to 2.50)3.27 (2.06 to 5.18)4.32 (2.73 to 6.83)6.67 (4.21 to 10.55)1.28 (1.22 to 1.34)<0.001
Risk of IFG
 Model 1*1.01.25 (0.94 to 1.66)1.70 (1.28 to 2.25)2.12 (1.60 to 2.80)3.89 (2.92 to 5.19)1.19 (1.15 to 1.24)<0.001
 Model 21.01.25 (0.94 to 1.67)1.69 (1.27 to 2.24)2.13 (1.61 to 2.83)3.94 (2.95 to 5.27)1.20 (1.16 to 1.24)<0.001
 Model 31.01.16 (0.87 to 1.55)1.50 (1.13 to 2.00)1.76 (1.31 to 2.35)3.09 (2.29 to 4.19)1.16 (1.12 to 1.20)<0.001
  • Data are OR (95% CI).

  • * Model 1 adjusted for age, gender, region and residence.

  • Model 2 further adjusted for smoking, alcohol drinking, physical activity and family history of diabetes.

  • Model 3 further adjusted for body mass index.