Patients' outcomes following intense occupational therapy compared with a single session control intervention in Alzheimer's patients and their carers
| Sample size | Baseline | 6 weeks | 16 weeks | 26 weeks | 52 weeks (postal carer rating) | |||||||||||
| COTiD | Control | COTiD | Control | COTiD | Control | Group difference | COTiD | Control | Group difference | COTiD | Control | Group difference | COTiD | Control | Group difference | |
| N | N | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (95% CI) | Mean (SD) | Mean (SD) | Mean (95% CI) | Mean (SD) | Mean (SD) | Mean (95% CI) | Mean (SD) | Mean (SD) | Mean (95% CI) | |
| Perceive, Recall, Plan and Perform System of Task Analysis independence 100 to 0* | 54 | 50 | 62.1 (26.8) | 64.6 (23.1) | 72.0 (27.1) | 66.7 (26.1) | −5.3 (−15.7 to 5.1) | 65.2 (30.3) | 67.4 (28.2) | 2.2 (−9.2 to 13.6) | 67.8 (30.1) | 71.1 (29.4) | 3.3 (−8.3 to 14.9) | – | – | – |
| Interview for Deterioration in Daily Living Activities in Dementiaperformance 44 to 0* | 54 | 50 | 15.4 (9.9) | 14.1 (10.1) | 14.3 (9.5) | 13.5 (10.3) | −0.8 (−4.6 to 3.1) | 15.8 (10.1) | 14.8 (10.1) | −1.0 (−5.0 to 2.9) | 16.9 (10.1) | 15.0 (10.3) | −1.9 (−5.8 to 2.1) | 21.1 (11.9) | 18.7 (11.6) | −2.4 (−7.1 to 2.3) |
| Interview for Deterioration in Daily Living Activities in Dementia initiative 0 to 36* | 54 | 50 | 16.0 (8.7) | 15.9 (8.4) | 15.0 (8.1) | 14.4 (8.7) | −0.6 (−3.9 to 2.7) | 15.5 (8.2) | 16.4 (9.1) | 0.9 (−2.5 to 4.3) | 16.1 (8.6) | 16.7 (9.3) | 0.6 (−2.9 to 4.1) | 20.1 (9.9) | 19.1 (10.1) | −1.0 (−5.0 to 3.0) |
| Cornell Scale for Depression in Dementia 0 to 38* | 41 | 37 | 13.2 (7.6) | 10.4 (6.3) | 12.7 (7.8) | 10.3 (6.1) | −2.4 (−5.5 to 0.8) | 11.4 (7.2) | 11.3 (6.6) | −0.1 (−3.2 to 3.0) | 12.3 (6.8) | 10.9 (6.3) | −1.3 (−4.3 to 1.6) | 13.8 (6.7) | 11.7 (6.7) | −2.0 (−5.1 to 1.0) |
| Dementia Quality of Life Instrument overall 5 to 1* | 49 | 45 | 2.8 (0.8) | 3.1 (0.8) | 2.9 (0.9) | 3.1 (0.6) | 0.3 (−0.04 to 0.6) | 2.8 (0.8) | 3.1 (0.9) | 0.3 (−0.02 to 0.6) | 2.9 (0.8) | 3.0 (0.8) | 0.2 (−0.1 to 0.5) | – | – | – |
| Short-Form 12 Health Survey Questionnaire physical 100 to 0* | 47 | 45 | 42.7 (10.0) | 45.0 (9.4) | 42.4 (11.4) | 45.4 (11.0) | 3.0 (−1.7 to 7.6) | 41.8 (9.2) | 45.1 (11.6) | 3.3 (−1.0 to 7.6) | 41.8 (11.3) | 44.8 (11.1) | 3.0 (−1.6 to 7.6) | – | – | – |
| Short-Form 12 Health Survey Questionnaire mental 100 to 0* | 47 | 45 | 49.3 (11.0) | 52.2 (9.3) | 50.3 (12.3) | 51.2 (9.9) | 0.9 (−3.7 to 5.6) | 51.8 (10.1) | 52.8 (9.5) | 1.1 (−3.0 to 5.1) | 53.1 (9.0) | 52.3 (10.6) | −0.8 (−4.9 to 3.3) | – | – | – |
* Range: positive to negative.
COTiD, Community Occupational Therapy in Dementia Programme.