Table 1

Baseline epidemiological characteristics between hypertonic-saline-treated and non-treated groups

Hypertonic saline (n=121)No hypertonic saline (n=303)p Value
Age, mean±SD33±1031±120.13
Male gender, n (%)37 (31%)196 (65%)<0.001
Body mass index, mean±SD20.8±0.721.9±5.70.001
Forced expiratory volume in 1 s (% predicted), mean±SD50±1246±230.016
Forced vital capacity (% predicted), mean±SD73±957±24<0.001
Use of recombinant human DNase, n (%)121 (100%)303 (100%)NA
Sputum positivity for Pseudomonas aeruginosa, n (%)60 (50%)211 (70%)<0.001
Sputum positivity for methicillin-resistant Staphylococcus aureus, n (%)60 (50%)97 (32%)0.001
Airway-clearance device (chest vest or flutter valve), n (%)80 (93%)143 (97%)
Hospitalisation/home intravenous antibiotics, n (%)41 (52%)/41 (48%)88 (60%)/60 (40%)