Table 1

Study activities and timeline

Study procedure	Prior to day 1	In clinic Day 1		At home≤4 weeks (TWNB only)
Study procedure	Screening	Clinician	Self-sampling	Self-sampling
Eligibility assessment	X
Informed consent		X
Demographics		X
Medical history		X
Vaginal swab			X*	X*
Anal swab			X	X
Oral rinse			X	X
Urine			X
Cervical swab		X (TMNB only)
Survey			X (TMNB only)	X
Adverse event assessment		X	X	X

*All TMNB and only TWNB who have undergone vaginoplasty.
TMNB, transmasculine and non-binary people with a cervix; TWNB, transfeminine and non-binary people assigned male at birth.