Table 1

Organisation of study visits

		Intervention—Induction phase
Visits	Visit 1	Visit 2	Visit 3	Visit 4	Visit 5	Visit 6	Visit 7	Visit 8	Visit 9	Visit 10	Visit 11	Visit 12	Visit 13	Visit 14
Week	0	1	1	1	2	2	2	3	3	3	4	4	4	5
Assessments	X													X
CPET	X												X
Assessment of AE		X	X	X	X	X	X	X	X	X	X	X	X	X
Supervised aerobic exercise		X	X	X	X	X	X	X	X	X	X	X
Supervised resistance training		X	X	X	X	X	X	X	X	X	X	X	X
RFH-GA	X													X
Nutrition Intervention		X						X
Stress and anxiety reduction intervention		X						(X)
	Intervention—Maintenance phase						Intervention—Maintenance phase
Visit number	Visit 15	Visit 16	Visit 17	Visit 18	Visit 19	Visit 20	Visit 21	Visit 22	Visit 23	Visit 24	Visit 25	Visit 26
Week	6	8	10	12	14	15	16	18	20	22	24	25
Assessments						X						X
CPET					X						X
Assessment of AE	X	X	X	X	X	X	X	X	X	X	X	X
Supervised aerobic exercise	X	X	X	X			X	X	X	X
Supervised resistance training	X	X	X	X	X		X	X	X	X	X
RFH-GA						X						X
Nutrition Intervention	X						X
Stress and anxiety reduction intervention	(X)						(X)

AE, adverse event; CPET, cardiopulmonary exercise testing; RFH-GA, Royal Free Hospital-Global Assessment.