Payment amounts by top 10 companies
| Variables | Payment amounts (%), US$ | Major products used for bipolar and major depressive disorders (generic name) | |||||
| 2016 | 2017 | 2018 | 2019 | 2020 | Overall | ||
| Total amounts of payments | 959 289 (100) | 872 245 (100) | 769 649 (100) | 743 295 (100) | 697 170 (100) | 4 041 648 (100) | |
| Top 10 companies making the largest payment amounts | |||||||
| Sumitomo Pharma | 180 436 (18.8) | 105 531 (12.1) | 127 847 (16.6) | 106 975 (14.4) | 174 243 (25.0) | 695 031 (17.2) | Effexor (venlafaxine, copromotion with Pfizer Japan) Erispan (fludiazepam) Excegran (zonisamide) Halomonth (haloperidol decanoate) Mystan (clobazam) Noritren (nortriptyline) Landosen (clonazepam) Latuda (lurasidone) Lonasen Tapes (blonanserin) Lullan (perospirone) Sediel (tandospirone) Serenace (haloperidol) |
| Eisai | 45 779 (4.8) | 78 418 (9.0) | 52 244 (6.8) | 80 026 (10.8) | 151 856 (21.8) | 408 323 (10.1) | Dayvigo (lemborexant) Spiropyran (spiperone) |
| MSD | 122 880 (12.8) | 83 528 (9.6) | 79 420 (10.3) | 57 679 (7.8) | 14 020 (2.0) | 357 526 (8.8) | Belsomra (suvorexant) Remeron (mirtazapine) Reslin (trazodone) Tetramide (mianserin) |
| Otsuka Pharmaceutical | 64 794 (6.8) | 73 028 (8.4) | 64 161 (8.3) | 86 679 (11.7) | 65 976 (9.5) | 354 638 (8.8) | Abilify (aripiprazole) Rexulti (brexpiprazole) |
| Takeda Pharmaceutical | 69 017 (7.2) | 78 990 (9.1) | 45 019 (5.8) | 71 206 (9.6) | 73 138 (10.5) | 337 370 (8.3) | Depas (etizolam) Eurodin (estazolam) Trintellix (vortioxetine) |
| Pfizer Japan | 78 269 (8.2) | 106 973 (12.3) | 65 996 (8.6) | 46 086 (6.2) | 14 247 (2.0) | 311 571 (7.7) | Amoxan (amoxapine) Desyrel (trazodone) Effexor (venlafaxin) Halcion (triazolam) Jzoloft (sertraline) Wypax (lorazepam) Mirtazapine (generic mirtazapine) |
| Mitsubishi Tanabe Pharma | 58 501 (6.1) | 47 295 (5.4) | 61 056 (7.9) | 59 114 (8.0) | 25 789 (3.7) | 251 755 (6.2) | Clofekton (clocapramine hydrochloride) Contomin (chlorpromazine) Levotomin (levomepromazine) Rize (clotiazepam) |
| Eli Lilly Japan | 56 337 (5.9) | 60 899 (7.0) | 59 231 (7.7) | 36 314 (4.9) | 38 130 (5.5) | 250 910 (6.2) | Strattera (atomoxetine) Zyprexa (olanzapine) Zyprexa Zydis (olanzapine) |
| Meiji Seika Pharma | 75 608 (7.9) | 53 110 (6.1) | 57 841 (7.5) | 27 228 (3.7) | 24 235 (3.5) | 238 023 (5.9) | Depromel (fluvoxamine) Reflex (mirtazapine) Sycrest (asenapine) Aripiprazole (generic aripiprazole) |
| Mochida Pharmaceutical | 35 768 (3.7) | 29 405 (3.4) | 31 597 (4.1) | 41 378 (5.6) | 17 209 (2.5) | 155 356 (3.8) | Lexapro (escitalopram) Tecipul (setiptiline) Zolpidem (generic zolpidem) |