Quality assessment
| Unit of analysis | Instrument | Extraction vs evaluation |
| Underlying primary studies | Eg, Cochrane Risk of Bias Tool | Extracted from systematic reviews |
| Overall evidence base of outcomes within included systematic reviews | Eg, GRADE | Extracted from systematic reviews if available, independent evaluation if possible |
| Included systematic reviews | AMSTAR 2 | Independent evaluation |
AMSTAR 2, A MeaSurement Tool to Assess systematic Reviews; GRADE, Grading of Recommendations Assessment, Development and Evaluation.