Table 1

Study characteristics

Study IDCountryStudy designSample sizeDelivery modelUnique model components
Rao (2022)South AfricaRetrospective cohort2776Facility basedNR
Witte et al 31 UgandaCross-sectional542Community basedHotspots
Hensen et al 19 ZimbabweMixed methods963Facility basedStatic clinics, community mobilisation and referrals (DREAMS Initiative)
Jana et al 24 IndiaDemonstration trial678Home delivery & facility basedWeekly pick-ups and home delivery
Little et al 33 South AfricaMixed methods600Facility basedTraining of staff and peers
Leis et al 22 KenyaCross-sectional220Facility basedAvailability of free PrEP
Franks et al 21 DRCDemonstration project469Facility basedLeveraged existing facility staff and was supported by the PrEP coordinator
Chimbindi (2021)South AfricaMixed methods2184Community basedHotspots
Nalukwago (2021)UgandaCross-sectional126Facility basedDrug pick-ups
Matambanadzo et al 30 ZimbabweFollow-up study19 407Community basedPeer led, used virtual appointment platforms, had multimonth refills, post-initiation support, unique alphanumerical identifier
Kagaayi et al 26 UgandaRetrospective cohort1332Facility basedHealth facilities and community outreach
Diantha (2020)South AfricaCross-sectional299Facility basedImplementers of oral PrEP
Sarr et al 25 SenegalDemonstration trial267Facility basedClinic drug refills
Geldsetzer (2020)EswatiniStepped-wedge RCT and qualitative survey2232Facility basedPrEP promotion using videos and T-shirts, flip charts and booklets
Becquet (2020)Ivory CoastMixed methods1000Community basedUse of community-based organisations
Guure (2020)GhanaCross-sectional998Community basedVenue, day and time scheduling at different FSW venues
Sushena (2020)IndiaDemonstration trial647Community basedIntense community preparedness using peers and leaders
Mudzviti (2020)ZimbabweCross-sectional131NRNR
Chimbindi (2019)South AfricaCohort2184Community basedTargeted rollout (demand for, access to and community members’ attitude toward PrEP)
Mboup et al 27 BeninProspective cohort256Facility basedDrug refills at the facility and in the community, integration of ART with PrEP
Cowan et al 20 ZimbabweCluster randomised trial2883Facility basedCommunity mobilisation, legal advice, trained peers, drop-in centres and telephone reminders (Sister’s Programme)
Eakle et al 28 South AfricaRetrospective cohort219Facility basedClinic pick-ups
Alary (2016)BeninNR256Community basedNR

  • ART, antiretroviral treatment; DRC, Democratic Republic of Congo; FSW, female sex worker; NR, not reported; PrEP, pre-exposure prophylaxis; RCT, randomised controlled trial.