Table 4

Pregnancy outcomes—Cox proportional hazard models

GLP1-RA group vs diabetic reference groupGLP1-RA group vs overweight/obese reference group
HR (95% CI)HRadj (95% CI)*HR (95% CI)HRadj (95% CI)*
Pregnancy loss†1.10 (0.65 to 1.89)1.67 (0.93 to 3.01)0.92 (0.56 to 1.49)0.80 (0.48 to 1.33)
Pregnancy termination‡2.92 (1.18 to 7.20)3.89 (1.48 to 10.2)1.79 (0.89 to 3.62)1.39 (0.66 to 2.93)
  • *Adjusted for maternal age, tobacco use, folate intake, past abortion or termination history.

  • †Spontaneous abortions and stillbirths.

  • ‡Elective or medical termination of pregnancy.

  • GLP1-RA, glucagon-like peptide 1 receptor agonists; HRadj, adjusted HR.