Table 1

Inclusion and exclusion criteria for the systematic review

Inclusion criteriaExclusion criteria
  • All randomised controlled trials and cohort studies with >250 participants

  • Including patients with breast cancer receiving neoadjuvant systematic anticancer therapy of any regimen/modality followed by loco-regional therapy (surgery and/or radiotherapy)

  • Published in English between 1 January 2018 and 8 September 2023

  • Reporting at least one locoregional outcome relating to surgery and/or radiotherapy

  • Not primary research studies

  • Studies published prior to 1 January 2018

  • Studies including any neoplasm other than breast cancer

  • Studies including metastatic or locally advanced/unresectable breast cancer or evaluating palliative chemotherapy

  • Cohort studies with <250 patients

  • Studies not published in English

  • Studies not reporting at least one locoregional outcome