Table 1

Schedule of assessments for N-of-1 trial

PretrialPostallocationPost-Trial
Cycle Cycle 1 Cycle 2 Cycle 3 Cycle 4
Time point Baseline Allocated Week 1 (M–F) Week 2
(M–F)
Week 3 (M–F) Week 4 (M–F) Week 5 (M–F) Week 6 (M-F) Week 7 (M-F) Week 8 (M-F)
Intervention example sequences
(sequence 1)
PAAPPAPA
Sequences 2–16APAPPAAP
OutcomeFASD diagnostic assessment, baseline demographicsDaily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Daily: T, P, WFIRS, TPA
Weekly: SE
Treatment decision
  • FASD diagnostic assessment: as per the Australian guide to the diagnosis of FASD (1). Bold letter indicates the main N-of-1 outcome, daily (M–F).

  • Note: this sequence listed is an example of one of the many possible sequences in the trial (randomly allocated).

  • FASD, fetal alcohol spectrum disorder; M–F, Monday–Friday; P, parent-rated Conners 3 early childhood; T, teacher-rated Conners 3 early childhood; TPA, top problems assessment; WFIRS, Weiss Functional Rating Scale.