Table 1

Schedule of assessments

ScreeningDouble-blind period
Screening/ baseline assessmentRandomisation1–5 months6 months
Study visit (onsite or telehealth)XX
Telephone interview (monthly)X
Informed consentX
Knee X-rayX
Blood testX
Medical history/conditionsXX
MedicationXX
Employment and educationX
Smoking and alcoholX
Questionnaires
 Knee VASXXX
 WOMACXX
 PainDETECTXX
 Hand VASXXX
 Multisite painXX
 AQoLXX
 IPAQXX
Physical examination
 Height, weight*XX
Compliance and safety (adverse events)XX
Dispense medicationX
  • *Height and weight will be self-reported if the visit is via telehealth.

  • AQoL, assessment of quality of life; IPAQ, international physical activity questionnaire; VAS, Visual Analogue Scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.