Table 1

Schedule of screening, measurement and clinical data collection

Inspection itemsStudy period
Screening periodMeasurement and clinical data collection
Initial assessment of patients
Signing the informed consent form
Demographic data collection
Medical history data collection
Routine blood test
Liver function
Blood coagulation function
Blood lipid
Detection of AFP, DCP and AFP-L3
Viral hepatitis type B testingSerum markers of HBV
Concentration of HBV DNA
Viral hepatitis type C testingSerum markers of HCV
Concentration of HCV DNA
Imaging tests of the liver
Transabdominal ultrasound
Sample collection for blood polygene methylation testing
Detection of blood polygene methylation
  • AFP, α-fetoprotein; AFP-L3, the Lens culinaris agglutinin A-reactive fraction of AFP; DCP, des-γ-carboxy-prothrombin; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus.