Characteristics | Age-standardised prevalence rate per 100 000 population | Age-standardised death rate per 100 000 population | Age-standardised DALY rate per 100 000 population | ||||||
1990 no (95% UI) | 2019 no (95% UI) | EAPC no (95% CI) | 1990 no (95% UI) | 2019 no (95% UI) | EAPC no (95% CI) | 1990 no (95% UI) | 2019 no (95% UI) | EAPC no (95% CI) | |
Global | 73.23 (63.86 to 83.63) | 59.25 (52.78 to 66.47) | −0.66 (−0.75 to −0.57) | 0.67 (0.57 to 0.78) | 0.54 (0.46 to 0.59) | −0.69 (−0.81 to −0.57) | 27.20 (21.70 to 32.39) | 20.15 (16.86 to 23.71) | −1.04 (−1.06 to −1.01) |
Sex | |||||||||
Male | 71.52 (62.12 to 81.89) | 59.30 (52.60 to 66.91) | −0.56 (−0.64 to −0.49) | 0.69 (0.56 to 0.88) | 0.56 (0.45 to 0.62) | −0.78 (−0.83 to −0.72) | 27.40 (21.78 to 33.22) | 20.64 (17.16 to 24.31) | −0.99 (−1.01 to −0.97) |
Female | 75.01 (65.67 to 85.45) | 59.33 (52.89 to 66.18) | −0.74 (−0.85 to −0.64) | 0.63 (0.50 to 0.74) | 0.52 (0.43 to 0.58) | −0.64 (−0.80 to −0.47) | 27.09 (20.30 to 32.42) | 19.70 (16.16 to 23.49) | −1.09 (−1.12 to −1.06) |
SDI quintile | |||||||||
High | 200.83 (176.43 to 226.92) | 183.14 (166.58 to 201.17) | −0.34 (−0.43 to −0.24) | 0.72 (0.65 to 0.85) | 0.84 (0.69 to 0.92) | 0.82 (0.64 to 1.01) | 43.95 (34.13 to 55.06) | 42.93 (33.66 to 53.08) | 0.00 (−0.06 to 0.05) |
High middle | 82.41 (71.42 to 95.06) | 73.85 (65.38 to 83.09) | −0.32 (−0.47 to −0.18) | 0.52 (0.46 to 0.60) | 0.38 (0.34 to 0.43) | −1.17 (−1.32 to −1.02) | 25.92 (21.34 to 30.93) | 19.34 (15.59 to 23.73) | −1.12 (−1.17 to −1.07) |
Middle | 22.50 (19.00 to 26.62) | 30.57 (25.70 to 36.01) | 1.25 (1.04 to 1.47) | 0.57 (0.40 to 0.74) | 0.31 (0.26 to 0.34) | −2.44 (−2.59 to −2.29) | 18.11 (14.29 to 21.72) | 11.61 (9.70 to 13.71) | −1.63 (−1.68 to −1.58) |
Low middle | 19.02 (15.75 to 22.93) | 20.94 (17.41 to 25.11) | 0.52 (0.40 to 0.64) | 0.74 (0.47 to 1.06) | 0.48 (0.38 to 0.58) | −1.75 (−1.90 to −1.60) | 23.29 (16.18 to 30.53) | 15.37 (12.47 to 18.32) | −1.58 (−1.65 to −1.51) |
Low | 12.40 (10.21 to 15.06) | 12.85 (10.64 to 15.81) | 0.29 (0.19 to 0.39) | 0.67 (0.48 to 0.99) | 0.55 (0.43 to 0.70) | −0.80 (-0.86 to -0.74) | 22.19 (14.49 to 29.80) | 17.19 (13.57 to 21.70) | −0.94 (-0.99 to -0.89) |
GBD region | |||||||||
Andean Latin America | 16.55 (14.08 to 19.39) | 17.09 (14.60 to 19.88) | 0.06 (0.03 to 0.10) | 0.54 (0.36 to 0.71) | 0.26 (0.20 to 0.32) | −2.74 (−3.16 to −2.32) | 26.36 (15.78 to 38.96) | 9.83 (7.75 to 12.19) | −3.68 (−4.17 to −3.18) |
Australasia | 108.86 (92.21 to 126.63) | 156.30 (137.65 to 177.07) | 0.83 (0.61 to 1.05) | 0.54 (0.47 to 0.64) | 0.72 (0.53 to 0.83) | 1.77 (1.41 to 2.13) | 26.19 (20.48 to 32.91) | 34.98 (26.87 to 44.64) | 0.93 (0.75 to 1.12) |
Caribbean | 27.93 (23.96 to 32.85) | 26.31 (22.13 to 31.28) | −0.05 (−0.13 to 0.03) | 0.56 (0.44 to 0.69) | 0.42 (0.31 to 0.53) | −1.24 (−1.41 to −1.08) | 23.38 (16.68 to 34.05) | 18.21 (13.08 to 24.76) | −0.91 (−1.06 to −0.76) |
Central Asia | 76.86 (64.98 to 91.56) | 78.72 (66.39 to 93.40) | 0.09 (0.05 to 0.12) | 0.39 (0.30 to 0.46) | 0.32 (0.28 to 0.37) | −1.00 (−1.12 to −0.89) | 26.11 (21.03 to 31.71) | 22.26 (18.04 to 27.31) | −0.70 (−0.76 to −0.65) |
Central Europe | 208.99 (179.90 to 243.75) | 160.49 (145.58 to 176.95) | −1.25 (−1.64 to −0.87) | 0.46 (0.43 to 0.52) | 0.47 (0.40 to 0.55) | 0.30 (0.17 to 0.44) | 46.28 (36.16 to 57.91) | 35.84 (27.66 to 44.67) | −1.08 (−1.37 to −0.78) |
Central Latin America | 37.84 (32.42 to 44.16) | 32.59 (27.93 to 38.07) | −0.49 (−0.58 to −0.41) | 0.32 (0.28 to 0.35) | 0.37 (0.30 to 0.43) | 0.98 (0.68 to 1.28) | 14.84 (12.69 to 17.31) | 14.68 (12.25 to 17.41) | 0.32 (0.08 to 0.56) |
Central sub-Saharan Africa | 8.22 (6.76 to 10.11) | 8.21 (6.80 to 10.11) | −0.14 (−0.33 to 0.06) | 0.72 (0.51 to 1.03) | 0.60 (0.45 to 0.83) | −0.69 (−0.77 to −0.60) | 22.26 (14.75 to 32.74) | 17.77 (12.98 to 24.27) | −0.79 (−0.88 to −0.70) |
East Asia | 22.51 (18.72 to 26.72) | 46.22 (39.36 to 53.98) | 2.79 (2.41 to 3.18) | 0.86 (0.59 to 1.14) | 0.31 (0.25 to 0.35) | −3.98 (−4.33 to −3.63) | 24.23 (17.74 to 29.83) | 13.08 (10.31 to 16.19) | −2.31 (−2.48 to −2.15) |
Eastern Europe | 88.07 (75.40 to 103.25) | 82.82 (70.77 to 96.45) | 0.01 (−0.11 to 0.14) | 0.49 (0.38 to 0.56) | 0.51 (0.43 to 0.58) | −0.25 (−0.53 to 0.04) | 27.68 (21.86 to 33.71) | 26.67 (21.96 to 32.46) | −0.30 (−0.45 to −0.14) |
Eastern sub-Saharan Africa | 6.27 (5.25 to 7.68) | 7.21 (6.01 to 8.82) | 0.46 (0.42 to 0.50) | 0.72 (0.52 to 1.01) | 0.69 (0.50 to 0.93) | −0.12 (−0.20 to −0.05) | 22.58 (16.13 to 33.35) | 19.44 (14.69 to 25.63) | −0.46 (−0.54 to −0.39) |
High-income Asia Pacific | 126.18 (105.73 to 149.32) | 210.54 (183.69 to 239.68) | 1.04 (0.68 to 1.41) | 0.40 (0.24 to 0.47) | 0.13 (0.11 to 0.18) | −4.29 (−4.64 to −3.93) | 26.43 (19.87 to 33.86) | 34.55 (23.75 to 46.76) | 0.35 (0.11 to 0.60) |
High-income North America | 346.93 (303.63 to 392.66) | 209.60 (195.48 to 224.46) | −1.32 (−1.75 to −0.89) | 0.68 (0.61 to 0.83) | 0.97 (0.79 to 1.05) | 1.43 (1.15 to 1.72) | 65.62 (48.61 to 84.95) | 51.27 (40.90 to 62.35) | −0.46 (−0.72 to −0.20) |
North Africa and Middle East | 36.27 (31.06 to 41.91) | 48.26 (40.98 to 56.94) | 0.97 (0.84 to 1.10) | 0.34 (0.24 to 0.49) | 0.26 (0.22 to 0.30) | −0.86 (−0.93 to −0.80) | 14.36 (10.79 to 18.73) | 13.26 (10.60 to 16.47) | −0.30 (−0.34 to −0.25) |
Oceania | 4.34 (3.51 to 5.20) | 3.87 (3.16 to 4.71) | −0.54 (−0.72 to −0.35) | 0.63 (0.42 to 0.86) | 0.44 (0.33 to 0.60) | −1.41 (−1.50 to −1.32) | 20.60 (13.34 to 28.78) | 14.93 (10.45 to 21.01) | −1.29 (−1.38 to −1.20) |
South Asia | 19.68 (15.98 to 24.40) | 20.11 (16.38 to 24.81) | 0.26 (0.10 to 0.42) | 0.69 (0.47 to 1.06) | 0.44 (0.33 to 0.57) | −1.91 (−2.07 to −1.74) | 21.48 (14.77 to 29.47) | 14.00 (10.70 to 17.52) | −1.68 (−1.78 to −1.58) |
Southeast Asia | 4.40 (3.55 to 5.35) | 6.69 (5.52 to 8.04) | 1.58 (1.27 to 1.90) | 0.50 (0.27 to 0.66) | 0.28 (0.21 to 0.33) | −2.36 (−2.52 to −2.19) | 13.16 (8.47 to 15.9) | 7.45 (6.06 to 8.76) | −2.29 (−2.44 to −2.15) |
Southern Latin America | 19.22 (15.96 to 22.60) | 20.53 (17.36 to 24.24) | 0.28 (0.08 to 0.49) | 0.31 (0.27 to 0.34) | 0.28 (0.25 to 0.34) | −0.46 (−0.62 to −0.30) | 11.10 (9.69 to 12.66) | 10.06 (8.61 to 11.94) | −0.40 (−0.50 to −0.31) |
Southern sub-Saharan Africa | 10.44 (8.67 to 12.74) | 11.78 (9.83 to 14.31) | 0.53 (0.45 to 0.61) | 0.42 (0.33 to 0.53) | 0.44 (0.36 to 0.51) | 0.25 (−0.16 to 0.65) | 15.11 (10.88 to 18.87) | 13.66 (11.37 to 15.90) | −0.12 (−0.44 to 0.20) |
Tropical Latin America | 65.14 (57.26 to 74.08) | 47.34 (41.21 to 54.02) | −0.87 (−1.08 to −0.65) | 0.47 (0.41 to 0.51) | 0.44 (0.40 to 0.51) | 0.03 (−0.14 to 0.21) | 23.37 (19.94 to 27.30) | 19.26 (16.53 to 22.44) | −0.44 (−0.61 to −0.26) |
Western Europe | 156.46 (139.89 to 173.69) | 188.22 (169.47 to 207.48) | 0.37 (0.26 to 0.48) | 0.82 (0.73 to 1.04) | 1.11 (0.87 to 1.23) | 1.51 (1.27 to 1.75) | 39.24 (31.18 to 48.16) | 46.79 (36.98 to 57.57) | 0.59 (0.49 to 0.69) |
Western sub-Saharan Africa | 8.49 (7.03 to 10.33) | 10.09 (8.38 to 12.23) | 0.78 (0.66 to 0.90) | 0.56 (0.33 to 0.91) | 0.5 (0.35 to 0.67) | −0.37 (−0.46 to −0.28) | 19.69 (11.64 to 30.47) | 16.77 (11.61 to 22.73) | −0.57 (−0.66 to −0.48) |
DALY, disability-adjusted life-year; EAPC, estimated annual percentage change; GBD, Global Burden of Disease; SDI, Socio-demographic Index; UI, uncertainty interval.