DV: birth weight | ELFE (FR) | Raine Study (AU) | BiB (UK) | ||||||
M1 | M2 | M3 | M1 | M2 | M3 | M1 | M2 | M3 | |
Child controls | SES | Smoked | Child controls | SES | Smoked | Child controls | SES | Smoked | |
Mother’s region of origin | |||||||||
Host country-born (ref.) | |||||||||
Western EU/EEA | 24.7 | 21 | 20.8 | 37.2 | 30.3 | 25.3 | 45.1 | 42.9 | 30.3 |
Eastern EU | 97.9 | 94.6 | 85.2 | 38.1 | 37.5 | 29.9 | 44.1 | 34.6 | 29.5 |
Other Europe and Central Asia | 5.7 | 13.8 | 1 | −10.2 | 6.5 | −13.3 | |||
East Asia and Pacific | 145.3** | 142.3** | 131.8** | 13.8 | 10.1 | −9 | 115.3 | 96.1 | 80.2 |
South Asia | 211.9 | 211.1 | 244.7 | −51.2 | −54.2 | −87.4 | −74.1*** | −69.4*** | −94.4*** |
Middle East and North Africa | 60.4** | 86.6*** | 61.2** | 40.2 | 40.8 | 36.5 | −35.3 | −45 | −60.5 |
Sub-Saharan Africa | −38.5 | −9.8 | −40.1 | −35.8 | −46.9 | −67.9 | −53.8 | −58.1 | −82.1 |
Latin America and Caribbean | −7.1 | 8.7 | −14.5 | 165.7 | 165.7 | 126.6 | |||
North America | −67.6 | −76.6 | −56.7 | 374.4** | 373.1** | 354.9** | 108.7 | 86.4 | 70.2 |
Child controls | |||||||||
Female | −149.5*** | −149.2*** | −150.3*** | −128.2*** | −128.3*** | −122.4*** | −143.1*** | −141.4*** | −141.9*** |
Plural birth† | −372.7*** | −374.2*** | −378.6*** | 0 | 0 | 0 | −319.7*** | −313.2*** | −318.7*** |
Mother’s parity (birth order) | 50.3*** | 55.3*** | 54.2*** | 64.7*** | 65.1*** | 64*** | 52.8*** | 59.9*** | 57*** |
Gestational age | 23.7*** | 23.6*** | 23.5*** | 20.1*** | 20.2*** | 20.2*** | 25.4*** | 25.5*** | 25.3*** |
Mother controls | |||||||||
Height | 9.1*** | 8.5*** | 8.8*** | 10.6*** | 10.3*** | 10.6*** | 11.9*** | 11.7*** | 11.9*** |
Pre-pregnancy weight | 4.7*** | 5*** | 4.9*** | 5.7*** | 5.8*** | 5.6*** | 5.6*** | 5.6*** | 5.6*** |
SES | |||||||||
Education‡ | |||||||||
High (ref) | |||||||||
Medium | −11.8 | −3.2 | 12.6 | 13.7 | 0.1 | 2.2 | |||
Low | −34.4 | −15.1 | −6.5 | 13.7 | −17.4 | −13.6 | |||
Household income quintiles§ | |||||||||
1st quintile (ref.) | |||||||||
2nd quintile | 51.2*** | 43.8*** | −4.8 | 7.6 | 2.4 | −6.1 | |||
3rd quintile | 49.6*** | 32.2* | −35.3 | −15.1 | −44.4 | −33.5 | |||
4th quintile | 55.1*** | 34.4* | −37.1 | 2.3 | −43.7* | −35.7 | |||
5th quintile | 58.4*** | 33.9* | −63.5** | −32.2 | |||||
Mother smoked (pregnancy) | −119.8*** | −157.5*** | −108.9*** | ||||||
Constant | −5043*** | −4992*** | −4965*** | −4264*** | −4212*** | −4220*** | −6050*** | −5990*** | −5984*** |
N | 12 419 | 12 419 | 12 419 | 2310 | 2310 | 2310 | 4141 | 4141 | 4141 |
R2 | 0.358 | 0.36 | 0.369 | 0.38 | 0.38 | 0.4 | 0.485 | 0.488 | 0.492 |
DV: birth weight | ABCD (NL) | Gen R (NL) | ||||
M1 | M2 | M3 | M1 | M2 | M3 | |
Child controls | SES | Smoked | Child controls | SES | Smoked | |
Mother’s region of origin | ||||||
Host country-born (ref.) | ||||||
Western EU/EEA | 7.8 | 10.5 | 0.8 | 32.3 | 40.5 | 34.3 |
Eastern EU | −99.4 | −83.2 | −90.1 | 68.3 | 99.1 | 78.7 |
Other Europe and Central Asia | 28.8 | 67.7 | 68.5 | 11.5 | 58.5 | 52.2 |
East Asia and Pacific | 121.3* | 134.5* | 122.7* | 124** | 143.3** | 127.5** |
South Asia | −174.8** | −144.3* | −170.9** | 11.4 | 35.8 | 9.4 |
Middle East and North Africa | −6.2 | 25.7 | 1.7 | 20.5 | 63.3 | 38.8 |
Sub-Saharan Africa | −54.6 | −19.9 | −41.1 | −115.8** | −68.5 | −86.9* |
Latin America and Caribbean | −89.7** | −63* | −73.3* | −71.5** | −37.1 | −49.8* |
North America | −148.5 | −143.1 | −151 | −62.5 | −64.6 | −74.8 |
Child controls | ||||||
Female | −121.7*** | −123.4*** | −124*** | −107.8*** | −108.2*** | −109.1*** |
Plural birth† | 0 | 0 | 0 | −404.5*** | −409*** | −409.4*** |
Mother’s parity (birth order) | 80.3*** | 83.5*** | 82.3*** | 107.1*** | 110.9*** | 108.7*** |
Gestational age | 25.7*** | 25.5*** | 25.5*** | 26.1*** | 25.9*** | 25.9*** |
Mother controls | ||||||
Height | 10.9*** | 9.7*** | 9.7*** | 11.4*** | 10.2*** | 10.2*** |
Pre-pregnancy weight | 4.7*** | 5.3*** | 5.2*** | 4.6 | 5*** | 4.9*** |
SES | ||||||
Education‡ | ||||||
High (ref) | ||||||
Medium | −66.3*** | −54.7*** | −1.9 | −0.1 | ||
Low | −78.3*** | −56* | −49.7 | −43.6 | ||
Household income quintiles§ | ||||||
1st quintile (ref.) | ||||||
2nd quintile | 0.5 | 3.9 | 23.9 | 18 | ||
3rd quintile | −10.9 | −0.5 | 57.2** | 44.8* | ||
4th quintile | −37.9 | −23.5 | 93.6** | 73.4* | ||
5th quintile | 100.9** | 79.6* | ||||
Mother smoked (pregnancy) | −140.1*** | −77.3*** | ||||
Constant | −5827** | −5598*** | −5571*** | −6189*** | −6004*** | −5962*** |
N | 4072 | 4072 | 4072 | 5123 | 5123 | 5123 |
R2 | 0.398 | 0.402 | 0.408 | 0.456 | 0.461 | 0.465 |
M1: basic child and mother’s controls at birth. M2: M1 + socioeconomic status (SES) variables. M3: M2 + mother’s smoking during pregnancy.
*p<0.05, **p<0.01, ***p<0.001.
†The ABCD and the Raine Study cohorts only included single births in their sample.
‡Level of education based on the highest ongoing or completed education when the child was 0 years old (between >−1 year and <1 year). If more than one education level is reported within the defined time frame, we used the highest recorded education level. Classification according to International Standard Classification of Education 97/2011 (ISCED-97/2011). High: short cycle tertiary, bachelor, masters, doctoral or equivalent (ISCED-2011: 5-8, ISCED-97: 5-6). Medium: upper secondary, post-secondary non-tertiary (ISCED-2011: 3-4, ISCED-97: 3-4). Low: no education; early childhood; pre-primary; primary; lower secondary or second stage of basic education (ISCED-2011: 0-2, ISCED-97: 0-2).
§European Union Statistics on Income and Living Conditions income quintiles for all cohorts except for Raine (AU) and ABCD (NL) that measured household income in quartiles.
ABCD, Amsterdam Born Children and their Development; AU, Australia; BiB, Born in Bradford; EEA, European Economic Area; ELFE, Etude Longitudinale Française depuis l’Enfance; EU, European Union; Gen R, Generation R.