Table 1

Validation estimates of the pairwise comparisons among all study patients

ComparisonsValidation estimates (%)
PPV (95% CI)Sn (95% CI)NPV (95% CI)Sp (95% CI)
CDM vs EHRs
(n=874)
1.00 (0.99 to 1.00)0.93 (0.90 to 0.95)0.92 (0.89 to 0.95)1.00 (0.99 to 1.00)
CDM vs paper-based records0.54 (0.47 to 0.61)0.93 (0.86 to 0.97)0.96 (0.92 to 0.98)0.68 (0.62 to 0.73)
CDM vs re-diagnosis
(n=874)
1.00 (0.99 to 1.00)0.93 (0.90 to 0.95)0.92 (0.89 to 0.95)1.00 (0.99 to 1.00)
EHRs vs re-diagnosis
(n=806*)
1.00 (0.99 to 1.00)1.00 (0.99 to 1.00)1.00 (0.99 to 1.00)1.00 (0.99 to 1.00)
EHRs vs paper-based records
(n=336*)
0.53 (0.45 to 0.61)0.98 (0.92 to 1.00)0.99 (0.96 to 1.00)0.68 (0.62 to 0.74)
  • *Controls in the CDM that were identified as cases in EHRs were excluded from this analysis with their corresponding cases.

  • CDM, common data model; EHR, electronic health record; NPV, negative predictive value; PPV, positive predictive value; Sn, sensitivity; Sp, specificity.