Characteristics of the study sample and proportions and prevalence rate ratios of seropositivity and vaccination
No. of participants | No. of seropositive | No. of vaccinated participants | Model of antibodies of any origin (n=22 130) | Model of propensity to vaccination (n=22 130) | Model of antibodies in unvaccinated participants (n=7647) | ||||||||
% of seropositive | PRR (95% CI) | P value | % of vaccinated | PRR (95% CI) | P value | No. of participants | % of seropositive | PRR (95% CI) | P value | ||||
Sex | |||||||||||||
Female | 13 824 | 12 067 | 8844 | 87.29 | 1.00 | – | 63.98 | 1.00 | – | 4980 | 67.25 | 1.00 | – |
Male | 8306 | 7282 | 5639 | 87.67 | 0.99 | 0.012 | 67.89 | 1.05 | <0.001 | 2667 | 65.47 | 0.95 | <0.001 |
Age groups (years) | |||||||||||||
18–29 | 1491 | 1202 | 770 | 80.62 | 1.00 | – | 51.64 | 1.00 | – | 721 | 61.72 | 1.00 | – |
30–39 | 2774 | 2275 | 1534 | 82.01 | 1.02 | 0.215 | 55.30 | 1.03 | 0.420 | 1240 | 61.05 | 0.97 | 0.338 |
40–49 | 6700 | 5725 | 4177 | 85.45 | 1.01 | 0.194 | 62.34 | 1.17 | <0.001 | 2523 | 64.05 | 0.97 | 0.226 |
50–59 | 6049 | 5405 | 4061 | 89.35 | 1.03 | 0.003 | 67.14 | 1.23 | <0.001 | 1988 | 70.32 | 1.04 | 0.170 |
60+ | 5116 | 4742 | 3941 | 92.69 | 1.05 | <0.001 | 77.03 | 1.37 | <0.001 | 1175 | 74.81 | 1.09 | 0.001 |
Education | |||||||||||||
Basic | 1952 | 1744 | 1295 | 89.34 | 1.00 | – | 66.34 | 1.00 | – | 657 | 70.02 | 1.00 | – |
Medium | 8024 | 7119 | 5348 | 88.72 | 1.00 | 0.972 | 66.65 | 1.02 | 0.275 | 2676 | 69.21 | 1.02 | 0.337 |
High | 7544 | 6689 | 5223 | 88.67 | 1.00 | 0.890 | 69.23 | 1.08 | <0.001 | 2321 | 65.75 | 1.02 | 0.394 |
Missing | 4610 | 3797 | 2617 | 82.36 | 0.97 | 0.003 | 56.77 | 0.87 | <0.001 | 1993 | 63.07 | 1.00 | 0.923 |
COVID-19 in history | |||||||||||||
Seronegative | 11 352 | 8935 | 7882 | 78.71 | 1.00 | – | 69.43 | 1.00 | – | 3470 | 36.54 | 1.00 | – |
Seropositive— no symptoms | 5597 | 5374 | 3458 | 96.02 | 1.28 | <0.001 | 61.78 | 0.75 | <0.001 | 2139 | 90.04 | 3.45 | <0.001 |
Seropositive— with symptoms | 5181 | 5040 | 3143 | 97.28 | 1.32 | <0.001 | 60.66 | 0.78 | <0.001 | 2038 | 93.28 | 3.58 | <0.001 |
BMI | |||||||||||||
<18.5 | 256 | 197 | 134 | 76.95 | 1.00 | – | 52.34 | 1.00 | – | 122 | 52.46 | 1.00 | – |
18.5–24.9 | 8192 | 6964 | 5038 | 85.01 | 1.04 | 0.127 | 61.50 | 1.09 | 0.141 | 3154 | 63.44 | 1.17 | 0.009 |
25–29.9 | 8080 | 7167 | 5488 | 88.70 | 1.05 | 0.077 | 67.92 | 1.15 | 0.020 | 2592 | 68.36 | 1.18 | 0.006 |
30+ | 4802 | 4369 | 3312 | 90.98 | 1.06 | 0.046 | 68.97 | 1.16 | 0.013 | 1490 | 74.30 | 1.20 | 0.003 |
Missing | 800 | 652 | 511 | 81.50 | 0.98 | 0.515 | 63.88 | 1.18 | 0.017 | 289 | 52.25 | 0.95 | 0.498 |
NCDs in history | |||||||||||||
No | 13 888 | 11 958 | 8688 | 86.10 | 1.00 | – | 62.56 | 1.00 | – | 5200 | 65.23 | 1.00 | – |
Yes | 7152 | 6500 | 5161 | 90.88 | 1.00 | 0.818 | 72.16 | 1.06 | <0.001 | 1991 | 71.97 | 1.00 | 0.813 |
Missing | 1090 | 891 | 634 | 81.74 | 1.02 | 0.266 | 58.17 | 0.91 | 0.002 | 456 | 59.21 | 1.12 | 0.005 |
Vaccination | |||||||||||||
Vaccination—no | 7647 | 5095 | 0 | 66.63 | 1.00 | – | 0.00 | ||||||
Vaccination—yes | 14 483 | 14 254 | 14 483 | 98.42 | 1.52 | <0.001 | 100.00 | ||||||
Total | 22 130 | 19 349 | 14 483 | 7647 |
Seronegative=participants who were seronegative in the first phase of the study; seropositive—no symptoms=participants who were seropositive in the first phase of the study and did not suffer from the selected symptoms (temperature >37.5°C, cough, shortness of breath, loss of taste or olfactory sense, faintness); seropositive—with symptoms=participants who were seropositive in the first phase of the study and suffer from the selected symptoms (temperature >37.5°C, cough, shortness of breath, loss of taste or olfactory sense, faintness); NCDs in history=participant indicated that suffer from one or more from the following disorders (diabetes, hypertension, lung diseases (asthma, chronic obstructive pulmonary disease); vaccination—no=participant was not vaccinated against SARS-CoV-2 regardless of vaccine type or dose; vaccination—yes=participant was vaccinated against SARS-CoV-2 regardless of vaccine type or dose.
BMI, body mass index; NCD, non-communicable disease; PRR, prevalence rate ratio.