Table 2

Effect of TXA on VOEs

VOEsTXA n (%)Placebo n (%)OR (95% CI)P value for effectP value for heterogeneity
Any VOE386 (1.2)409 (1.3)0.94 (0.81 to 1.08)0.360.27
 Myocardial infarction79 (0.2)106 (0.3)0.73 (0.54 to 0.98)0.040.87
 Stroke131 (0.4)132 (0.4)0.99 (0.78 to 1.26)0.930.76
 Deep vein thrombosis85 (0.3)76 (0.2)1.12 (0.82 to 1.52)0.490.18
 Pulmonary embolism141 (0.4)139 (0.4)1.01 (0.80 to 1.28)0.910.18
  • TXA, tranexamic acid; VOEs, vascular occlusive events.