VOEs | TXA n (%) | Placebo n (%) | OR (95% CI) | P value for effect | P value for heterogeneity |
Any VOE | 386 (1.2) | 409 (1.3) | 0.94 (0.81 to 1.08) | 0.36 | 0.27 |
Myocardial infarction | 79 (0.2) | 106 (0.3) | 0.73 (0.54 to 0.98) | 0.04 | 0.87 |
Stroke | 131 (0.4) | 132 (0.4) | 0.99 (0.78 to 1.26) | 0.93 | 0.76 |
Deep vein thrombosis | 85 (0.3) | 76 (0.2) | 1.12 (0.82 to 1.52) | 0.49 | 0.18 |
Pulmonary embolism | 141 (0.4) | 139 (0.4) | 1.01 (0.80 to 1.28) | 0.91 | 0.18 |
TXA, tranexamic acid; VOEs, vascular occlusive events.