Multivariable analysis of the factors associated with dyslipidaemia control as per European Society of Cardiology/European Atherosclerosis Society criteria
| Baseline | First follow-up | Second follow-up | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (per 10 years increase) | 0.44 (0.34 to 0.57) | <0.001 | 0.34 (0.27 to 0.43) | <0.001 | 0.35 (0.28 to 0.44) | <0.001 |
| Man vs woman | 0.89 (0.58 to 1.36) | 0.599 | 0.48 (0.34 to 0.70) | <0.001 | 1.23 (0.85 to 1.79) | 0.273 |
| Swiss vs Non-Swiss | 1.30 (0.85 to 1.97) | 0.223 | 1.13 (0.79 to 1.64) | 0.503 | 1.01 (0.69 to 1.48) | 0.948 |
| Education | ||||||
| High | 1 (ref.) | 1 (ref.) | 1 (ref.) | |||
| Middle | 1.11 (0.54 to 2.27) | 0.782 | 0.83 (0.48 to 1.45) | 0.521 | 0.61 (0.35 to 1.07) | 0.087 |
| Low | 1.11 (0.59 to 2.11) | 0.738 | 0.81 (0.49 to 1.33) | 0.407 | 0.65 (0.40 to 1.07) | 0.093 |
| P value for trend | 0.738 | 0.407 | 0.093 | |||
| Married vs not married | 1.21 (0.80 to 1.82) | 0.374 | 1.21 (0.86 to 1.71) | 0.270 | 1.06 (0.74 to 1.5) | 0.759 |
| Body mass index categories | ||||||
| Normal | 1 (ref.) | 1 (ref.) | 1 (ref.) | |||
| Overweight | 0.59 (0.37 to 0.94) | 0.028 | 0.85 (0.57 to 1.26) | 0.413 | 0.61 (0.40 to 0.92) | 0.019 |
| Obese | 0.92 (0.54 to 1.56) | 0.753 | 0.96 (0.59 to 1.55) | 0.852 | 0.64 (0.40 to 1.04) | 0.074 |
| P value for trend | 0.753 | 0.852 | 0.074 | |||
| Smoking categories | ||||||
| Never | 1 (ref.) | 1 (ref.) | 1 (ref.) | |||
| Former | 1.54 (0.98 to 2.40) | 0.059 | 1.10 (0.75 to 1.62) | 0.618 | 1.38 (0.94 to 2.02) | 0.099 |
| Current | 0.63 (0.36 to 1.08) | 0.094 | 0.85 (0.52 to 1.39) | 0.512 | 1.04 (0.61 to 1.75) | 0.892 |
| P value for trend | 0.094 | 0.512 | 0.892 | |||
| Alcohol drinker (yes vs no) | 0.66 (0.42 to 1.03) | 0.068 | 0.91 (0.62 to 1.35) | 0.645 | 0.64 (0.43 to 0.94) | 0.024 |
| Antihypertensive treatment (yes vs no) | 1.05 (0.70 to 1.57) | 0.820 | 1.18 (0.82 to 1.69) | 0.368 | 0.77 (0.53 to 1.12) | 0.176 |
| Parental history (yes vs no) | 1.00 (0.64 to 1.56) | 0.998 | 1.08 (0.74 to 1.59) | 0.690 | 0.79 (0.53 to 1.18) | 0.256 |
| CVD risk | ||||||
| Other | 1 (ref.) | 1 (ref.) | 1 (ref.) | |||
| High | 1.25 (0.76 to 2.04) | 0.379 | 0.68 (0.45 to 1.04) | 0.074 | 1.42 (0.88 to 2.28) | 0.153 |
| Very high | 0.11 (0.06 to 0.18) | <0.001 | 0.12 (0.08 to 0.19) | <0.001 | 0.38 (0.25 to 0.59) | <0.001 |
| P lue for trend | <0.001 | <0.001 | <0.001 | |||
| LDL genetic risk score quartiles | ||||||
| First | 1 (ref.) | 1 (ref.) | 1 (ref.) | |||
| Second | 1.11 (0.65 to 1.89) | 0.696 | 0.97 (0.61 to 1.54) | 0.883 | 1.31 (0.81 to 2.12) | 0.264 |
| Third | 0.70 (0.41 to 1.19) | 0.185 | 0.96 (0.60 to 1.53) | 0.866 | 1.57 (0.97 to 2.51) | 0.064 |
| Fourth | 0.74 (0.43 to 1.25) | 0.259 | 1.07 (0.67 to 1.72) | 0.764 | 1.44 (0.89 to 2.32) | 0.133 |
| P value for trend | 0.107 | 0.781 | 0.099 | |||
| Hypolipidaemic drug treatment | ||||||
| Statins | 1.56 (0.18 to 13.8) | 0.690 | 1.00 (0.55 to 1.81) | 0.998 | 1.42 (0.81 to 2.51) | 0.223 |
| Fibrates | 0.67 (0.08 to 5.35) | 0.707 | 0.13 (0.04 to 0.43) | 0.001 | 1.20 (0.46 to 3.15) | 0.714 |
| Other | 0.94 (0.34 to 2.61) | 0.910 | 0.57 (0.31 to 1.04) | 0.067 | 0.71 (0.40 to 1.26) | 0.237 |
Data from the baseline (2003–2006), first (2009–2012) and second (2014–2017) follow-ups of the CoLaus|PsyCoLaus study, Lausanne, Switzerland.
Results are expressed as odds ratio and (95% CI). Statistical analysis wase done using logistic regression.
CVD, cardiovascular disease.