Multivariable analysis of the factors associated with dyslipidaemia control as per European Society of Cardiology/European Atherosclerosis Society criteria
| First follow-up | Second follow-up | |||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (per 10 years increase) | 0.31 (0.23 to 0.41) | <0.001 | 0.35 (0.27 to 0.47) | <0.001 |
| Man vs woman | 0.60 (0.39 to 0.92) | 0.018 | 1.40 (0.90 to 2.16) | 0.134 |
| Swiss vs Non-Swiss | 1.17 (0.76 to 1.80) | 0.474 | 1.16 (0.75 to 1.80) | 0.502 |
| Education | ||||
| High | 1 (ref.) | 1 (ref.) | ||
| Middle | 0.78 (0.40 to 1.53) | 0.476 | 1.08 (0.54 to 2.15) | 0.821 |
| Low | 0.88 (0.49 to 1.59) | 0.681 | 1.04 (0.57 to 1.90) | 0.895 |
| P value for trend | 0.681 | 0.895 | ||
| Married vs not married | 1.23 (0.82 to 1.83) | 0.317 | 1.19 (0.79 to 1.78) | 0.407 |
| Body mass index categories | ||||
| Normal | 1 (ref.) | 1 (ref.) | ||
| Overweight | 0.84 (0.52 to 1.35) | 0.474 | 0.56 (0.35 to 0.92) | 0.023 |
| Obese | 0.91 (0.53 to 1.58) | 0.749 | 0.54 (0.31 to 0.95) | 0.032 |
| P value for trend | 0.749 | 0.032 | ||
| Smoking categories | ||||
| Never | 1 (ref.) | 1 (ref.) | ||
| Former | 1.09 (0.70 to 1.71) | 0.695 | 1.21 (0.78 to 1.88) | 0.384 |
| Current | 0.84 (0.46 to 1.51) | 0.560 | 0.93 (0.51 to 1.71) | 0.820 |
| P value for trend | 0.560 | 0.820 | ||
| Alcohol drinker (yes vs no) | 0.79 (0.50 to 1.25) | 0.316 | 0.72 (0.46 to 1.12) | 0.146 |
| AntiHTA ttt (yes vs no) | 0.97 (0.63 to 1.51) | 0.903 | 0.80 (0.52 to 1.25) | 0.337 |
| Parental history (yes vs no) | 1.27 (0.80 to 2.02) | 0.310 | 0.76 (0.48 to 1.23) | 0.267 |
| CVD risk | ||||
| Other | 1 (ref.) | 1 (ref.) | ||
| High | 0.63 (0.39 to 1.02) | 0.061 | 1.32 (0.76 to 2.31) | 0.327 |
| Very high | 0.08 (0.05 to 0.14) | <0.001 | 0.35 (0.21 to 0.58) | <0.001 |
| P value for trend | <0.001 | <0.001 | ||
| LDL genetic risk score quartiles | ||||
| First | 1 (ref.) | 1 (ref.) | ||
| Second | 0.90 (0.53 to 1.54) | 0.707 | 1.67 (0.95 to 2.93) | 0.076 |
| Third | 0.89 (0.52 to 1.52) | 0.665 | 1.79 (1.04 to 3.07) | 0.036 |
| Fourth | 1.11 (0.65 to 1.92) | 0.696 | 1.64 (0.93 to 2.86) | 0.085 |
| P value for trend | 0.725 | 0.085 | ||
| Number of drugs (per one unit) | 1.15 (1.05 to 1.25) | 0.002 | 1.07 (0.99 to 1.15) | 0.069 |
| Statin generation | ||||
| First | 1 (ref.) | 1 (ref.) | ||
| Second | 1.90 (1.18 to 3.05) | 0.008 | 1.90 (1.08 to 3.36) | 0.026 |
| Third | 3.62 (1.65 to 7.92) | 0.001 | 2.18 (1.05 to 4.51) | 0.036 |
| P value for trend | 0.001 | 0.036 | ||
| Fibrates | NC | 2.55 (0.19 to 34.1) | 0.480 | |
| Other hypolipidaemic drugs | 0.90 (0.38 to 2.11) | 0.800 | 1.13 (0.51 to 2.51) | 0.762 |
Data from the first (2009–2012) and second (2014–2017) follow-ups of the CoLaus|PsyCoLaus study, Lausanne, Switzerland. Analysis was done taking into account statin generation.
Results are expressed as OR and (95% CI). Statistical analysis was done using logistic regression.
NC, not computable; antiHTA ttt, antihypertensive drug treatment.