Priority | The importance of what the specific intervention addresses, urgency of the problem. |
Desired effects | The extent of the desired effects of the intervention. |
Undesired effects | The extent of the undesired effects of the intervention. |
Desirable effects outweigh undesirable effects | Whether comparing the desired effects with the undesirable effects favours the intervention. |
Certainty of evidence on effects | The strength of the evidence and the confidence that the available evidence is adequate. |
Patient values and preferences | The extent to which practitioners believe the intervention or recommendation would meet patients’ preferences for how they might be affected. |
Resources required | Resources (money, time, human resources, etc) needed to implement the intervention. |
Certainty of evidence on resources required | Quality of the available evidence about the resources needed for the intervention, the strength of the evidence and the confidence that it is adequate. |
Cost-effectiveness | The economic impact of an intervention on the health system, government or society. |
Equity | Whether an intervention reduces inequalities in health if it reduces differences in effectiveness for disadvantaged populations. |
Acceptability | Level of acceptability by professionals due to, eg, ethical principles, distribution of effects and costs. |
Feasibility | Whether during day-to-day clinical practice the intervention can be implemented with available resources, infrastructure and training or with a minimal increase in resources. |
Measurability | Whether there is an indicator that measures the use of the intervention and whether it can be easily used in practice, without additional resources or with minimal additional resources. |