Table 3

‘Reference’ subsample exclusion criteria (healthy subsample)

Sample	Exclusion criteria
Minimum subsample of ‘reference’ children per site n=522	Below secondary maternal education (<6 years of schooling) Birth weight <2500 g Gestational age <37 completed weeks (259 days) and ≥42 completed weeks (294 days) (assessed by ultrasound) Undernutrition (weight for age, length for age, OR weight for height Z score of <–2 on the WHO Child Growth Standards) at the time of developmental assessment Known severe congenital birth defect History of birth asphyxia OR neonatal sepsis requiring hospitalisation Known neurodevelopmental disorder/disability (Severe visual problems, seizures, hearing impairment) OR other chronic health problems (ie, congenital heart disease)

Sample

Exclusion criteria

Minimum subsample of ‘reference’ children per site
n=522

Below secondary maternal education (<6 years of schooling)
Birth weight <2500 g
Gestational age <37 completed weeks (259 days) and ≥42 completed weeks (294 days) (assessed by ultrasound)
Undernutrition (weight for age, length for age, OR weight for height Z score of <–2 on the WHO Child Growth Standards) at the time of developmental assessment
Known severe congenital birth defect
History of birth asphyxia OR neonatal sepsis requiring hospitalisation
Known neurodevelopmental disorder/disability (Severe visual problems, seizures, hearing impairment) OR other chronic health problems (ie, congenital heart disease)