Table 2

Equivalence tables used in calculation of DDD and MED

Morphine mg/24 hours
103060120180240
Oxycodone mg/24 hours20*4080120160
Hydromorphone mg/24 hours48162432
Methadone mg/24 hours1020406080
Fentanyl ug/hour122550
Buprenorphine ug/hour10204052.270
Codeine mg/24 hours100240
Dihydrocodeine mg/24 hours100240
Tramadol mg/24 hours67200400
Tapentadol mg/24 hours25–5075–150150–300300–600†
  • *Conversion used in USA, Canada and Australia.

  • †The maximum recommended daily dose of Tapentadol prolonged release is 500 mg.

  • DDD, defined daily dose; MED, morphine equivalent dose.