Table 2

Cause of death: readjudication (RA) vs original NEJM publication

EVO
(RA)		EVO (NEJM)PLA
(RA)		PLA (NEJM)
Cardiac death
 Sudden cardiac43n.r.43n.r.
 Acute myocardial infarction36252730
 Heart failure31n.r.16n.r.
 Acute coronary syndrome1n.r.0n.r.
 Ischaemic heart disease1n.r.0n.r.
 Postinfarction cardiosclerosis1n.r.0n.r.
 Ventricular tachycardia0n.r.1n.r.
 Other causes0n.r.1n.r.
 Subtotal113n.r.88n.r.
Non-cardiac vascular death
 Stroke23312533
 Pulmonary embolism7n.r.7n.r.
 Cardiovascular haemorrhage5n.r.3n.r.
 Cardiovascular procedures1n.r.1n.r.
 Intestinal ischaemia1n.r.0n.r.
 Mesenteric ischaemia0n.r.1n.r.
 Subtotal37n.r.37n.r.
Non-cardiovascular death
 Malignancy80n.r.72n.r.
 Infection; includes sepsis34n.r.32n.r.
 Pulmonary7n.r.12n.r.
 Hepatobiliary3n.r.2n.r.
 Non-cardiovascular haemorrhage3n.r.2n.r.
 Non-cardiovascular procedure or surgery3n.r.0n.r.
 Pancreatic3n.r.1n.r.
 Suicide3n.r.3n.r.
 Trauma3n.r.6n.r.
 Renal2n.r.2n.r.
 Other causes9n.r.5n.r.
Cause of death after readjudication
 Death—cardiovascular150251125240
 Death—non-cardiovascular150n.r.137n.r.
 Death—undetermined144n.r.164n.r.
 Total444444426426

  • n.r., not reported; RA, data after readjudication.