Presence of WHO severity indicators in the study population
| System-wise, WHO severity markers | Patients with the marker (n) | Percentage among PTLC (n=1833) | Percentage among severe maternal outcomes (n=380) |
| Cardiovascular | |||
| Shock | 31 | 1.7 | 8.2 |
| Cardiopulmonary resuscitation | 30 | 1.6 | 7.9 |
| Use of continuous vasoactive drugs | 18 | 1.0 | 4.7 |
| pH <7.1 | 14 | 0.7 | 3.7 |
| Lactate >5 mmol/L | 4 | 0.2 | 1.1 |
| Cardiac arrest | 3 | 0.2 | 0.8 |
| Respiratory | |||
| Intubation and ventilation for >60 min not related to anaesthesia | 80 | 4.4 | 21.1 |
| Oxygen saturation <90% for >60 min | 48 | 2.6 | 12.6 |
| Respiratory rate >40 of <6 per minute | 18 | 1.0 | 4.7 |
| PaO2/FiO2 <200 mm Hg | 4 | 0.2 | 1.1 |
| Gasping | 1 | 0.1 | 0.3 |
| Renal | |||
| Oliguria, non-responsive to fluids or diuretics | 25 | 1.4 | 6.6 |
| Creatinine >300 mmol/L or >3.5 mg/dL | 24 | 1.3 | 6.3 |
| Dialysis for acute renal failure | 19 | 1.0 | 5.0 |
| Haematological/coagulation | |||
| Transfusion of >5 units of red cells | 108 | 5.9 | 28.4 |
| Acute thrombocytopaenia (<50 ×109/L platelets)/mm3 | 102 | 5.6 | 26.8 |
| Clotting failure | 93 | 5.0 | 24.5 |
| Hepatic | |||
| Bilirubin >100 mmol/L or >6.0 mg/dL | 26 | 1.4 | 6.8 |
| Jaundice in the presence of pre-eclampsia | 6 | 0.3 | 1.6 |
| Neurological | |||
| Uncontrollable fit/total paralysis | 19 | 1.0 | 5.0 |
| Loss of consciousness lasting >12 hours | 14 | 0.8 | 3.7 |
PaO2/FiO2, Ratio of the partial pressure of arterial oxygen (PaO2) to the fraction of inspired oxygen (FiO2); PTLC, potentially life-threatening conditions.