Table 4

Representative cohort studies from Nordic countries, the UK and the USA on the association of pre-eclampsia and risk of IHD or stroke

StudyN of women with/without history of pre-eclampsiaOrigin of the studyDuration of follow-up time (years)RR (95% CI) for IHDRR (95% CI) for stroke
Wikström et al2220 469*/383 081SwedenMean 151.7 (1.5 to 2.0)NR
Lykke et al2125 184/643 935DenmarkMedian 14.61.82 (1.65 to 2.00)1.53 (1.38 to 1.69)
Bhattacharya et al332026/23 935ScotlandNR1.18 (0.99 to 1.41)1.16 (0.93 to 1.45)
Männistö et al13242/8297Northern FinlandMean 39.41.36 (1.01 to 1.83)1.19 (0.68 to 2.09)
Haug et al341391/21 766NorwayMedian 181.78 (1.26 to 2.52)†1.46 (1.08 to 1.97) for women of 40–70 years of age
Leon et al3525 554/1 277 811UKMedian 9.251.67 (1.54 to 1.81)1.9 (1.53 to 2.35)
Garovic et al36298/596Minnesota, USAMedian 36.2 for pre-eclamptic women and 35.8 for referents1.85 (1.23 to 2.78)1.40 (0.89 to 2.22)
The present study31 728/92 168FinlandMean 341.52
(1.44 to 1.59)
1.40
(1.32 to 1.48)
  • *Including also women with gestational hypertension.

  • †Myocardial infarction only.

  • IHD, ischaemic heart disease; NR, not reported; RR, relative risk.