Total | Tobacco product types | Maximum standardised difference* | ||||

Exclusively cigarettes | Exclusively HTP | Dual use of cigarettes and HTP | Before | After | ||

N | 733 | 383 (52%) | 230 (31%) | 120 (16%) | ||

Age, mean±SD | 42.4±9.8 | 43.4±10 | 41.7±8.6† | 40.5±10† | 0.29 | 0.07 |

Male sex, n (%) | 689 (94) | 359 (94) | 218 (95) | 112 (93) | 0.04 | 0.01 |

Body mass index, median (IQR) | 23.5 (22–26) | 23.4 (21–25) | 23.5 (22–26)† | 23.8 (22–26) | 0.19 | 0.10 |

Years of smoking, median (IQR) | 22 (15–30) | 24 (16–30) | 20 (15–28)† | 20 (12–26)† | 0.33 | 0.11 |

Past attempt for cessation, n (%) | 453 (62) | 223 (58) | 157 (68)† | 73 (61) | 0.20 | 0.12 |

TDS score, median (IQR) | 7 (5–8) | 7 (6–8) | 7 (5–8) | 7 (6–9) | 0.06 | 0.10 |

Regular alcohol intake, n (%) | 121 (17) | 70 (18) | 32 (14) | 19 (16) | 0.11 | 0.07 |

Comorbidities | ||||||

Hypertension, n (%) | 57 (8) | 26 (7) | 18 (8) | 13 (11) | 0.16 | 0.00 |

Diabetes mellitus, n (%) | 5 (1) | 1 (0.3) | 2 (1) | 2 (2) | 0.28 | 0.15 |

Cardiovascular diseases, n (%) | 14 (2) | 6 (2) | 5 (2) | 3 (3) | 0.08 | 0.04 |

Mental disorders, n (%) | 21 (3) | 12 (3) | 7 (3) | 2 (2) | 0.08 | 0.09 |

Medications | ||||||

Varenicline, n (%) | 660 (90) | 336 (88) | 213 (93) | 111 (93) | 0.15 | 0.15 |

Nicotine, n (%) | 57 (8) | 37 (10) | 12 (5) | 8 (7) | 0.15 | 0.12 |

P values were calculated compared with the exclusively cigarette group by Mann-Whitney U test for continuous variables and by Fisher’s exact test for categorical variables.

*Maximum absolute standardised mean difference before and after inverse probability weighting.

†P<0.05.

TDS, Tobacco Dependence Screener.