Comparison of general conditions, laboratory test indexes and prognosis between the two groups
| Control group (n=120) | AAE group (n=102) | P value | |
| Gender ratio (male: female) | 44:76 | 39:63 | 0.810 |
| Age (years) | 71.88±8.84 | 72.20±7.97 | 0.779 |
| Antibiotic application time (days) | 7.10±2.01 | 7.24±3.04 | 0.693 |
| Composition of infection types: | |||
| Lung infection | 46.7% | 50% | 0.952 |
| Abdominal infection | 26.7% | 26.5% | |
| Urinary tract infection | 20% | 17.6% | |
| Others | 6.6% | 5.9% | |
| Composition of antibiotic types: | 0.133 | ||
| Cephalosporins | 43.3% | 41.2% | |
| Carbapenems | 26.7% | 28.4% | |
| Semi-synthetic penicillins | 16.7% | 14.7% | |
| Quinolones | 13.3% | 15.7% | |
| Haemoglobin (g/L) | 95.87±15.91 | 85.82±17.25 | <0.001 |
| Albumin (g/L) | 33.38±4.40 | 29.35±4.62 | <0.001 |
| White cell count (×109 /L) | 6.34±1.61 | 6.67±2.81 | 0.283 |
| CRP (mg/L) | 44.06±35.26 | 47.20±43.67 | 0.554 |
| Serum sodium (mmol/L) | 137.97±3.21 | 134.11±23.01 | 0.072 |
| Blood calcium (mmol/L) | 2.12±0.18 | 2.05±0.19 | 0.010 |
| Uric acid (μmol/L) | 342.17±86.57 | 313.74±79.12 | <0.001 |
| Blood phosphorus (mmol /L) | 1.52±0.38 | 1.24±0.40 | 0.012 |
| Ratio of patients with coronary heart disease | 96:24 | 90:12 | 0.097 |
| Ratio of patients with hypertension | 108:12 | 90:12 | 0.673 |
| Ratio of patients with diabetes | 60:60 | 54:48 | 0.662 |
| Case fatality rate (cases, %) | (19:120) 15.8 | (32:102) 31.4 | 0.006 |
| Rehospitalisation rate (cases, %) | (47:120) 39.2 | (57:102) 55.9 | 0.013 |
| Treatment cost (US$） | 3520.22±1036.16 | 5486.25±2292.06 | <0.001 |
AAE, antibiotic-associated encephalopathy; CRP, C reactive protein.