HR | 95% CI for HR | P value | ||
Lower | Upper | |||
HFpEF | 0.16 | |||
HFmrEF | 0.88 | 0.77 | 1.01 | 0.07 |
HFrEF | 0.98 | 0.86 | 1.12 | 0.76 |
<55 years of age | <0.001 | |||
55–64 years of age | 1.83 | 1.02 | 3.28 | 0.04 |
65–74 years of age | 2.19 | 1.27 | 3.76 | 0.005 |
75–84 years of age | 3.30 | 1.93 | 5.65 | <0.001 |
85–95 years of age | 4.08 | 2.37 | 7.03 | <0.001 |
>95 years of age | 4.72 | 2.49 | 8.93 | <0.001 |
Man/Women | 1.01 | 0.90 | 1.12 | 0.93 |
eGFR >60 mL/min/1.73 m2 | 0.008 | |||
eGFR 30–59 mL/min/1.73 m2 | 1.06 | 0.94 | 1.20 | 0.33 |
eGFR <30 mL/min/1.73 m2 | 1.31 | 1.10 | 1.56 | 0.002 |
NT-proBNP elevated | 1.66 | 1.18 | 2.32 | 0.003 |
Hypertension | 1.61 | 1.41 | 1.85 | <0.001 |
IHD | 2.09 | 1.82 | 2.39 | <0.001 |
CVI | 1.69 | 1.40 | 2.03 | <0.001 |
VHD | 1.85 | 1.59 | 2.16 | <0.001 |
Atrial fibrillation | 2.87 | 2.52 | 3.28 | <0.001 |
Diabetes mellitus | 1.61 | 1.38 | 1.87 | <0.001 |
COPD | 1.77 | 1.50 | 2.08 | <0.001 |
No HF treatment or diuretic only | <0.001 | |||
BB or RAASi | 0.71 | 0.62 | 0.82 | <0.001 |
BB and RAASi | 0.52 | 0.45 | 0.61 | <0.001 |
BB and RAASi and MRA | 0.55 | 0.47 | 0.65 | <0.001 |
BB, RAASi and MRA inhibitor treatment within one year after first diagnosed with HF.
ARB, angiotensin receptor blocker; BB, beta-blocker; COPD, chronic obstructive pulmonary disease; CVI, cerebrovascular insult; eGFR, estimated glomerular filtration rate; IHD, ischaemic heart disease; MRA, mineralocorticoid receptor antagonist; NT-proBNP, N-terminal pro-B-type natriuretic peptide; RAASI, renin-angiotensin-aldosterone system inhibitor; VHC, valvular heart disease.