Schedule of procedures and data collection for the U-PAIN cohort study
| Data collection | Prior to the clinical consultation | First clinical consultation | The research visit* baseline | After the research visit | Follow up*† at 12, 24, 36, 48, 60 months |
| Screened for eligibility | X | ||||
| Online survey of computerised PROMs, accessed through the Swedish healthcare online guide | X | X | |||
| Written information and an invitation to participate in the study by mail | X | ||||
| Telephone calls from research staff informing about the study and asking about any interest to participate | X | ||||
| Enrolment with signed informed written consent | X | ||||
| Clinical chronic pain diagnoses retrieved from medical records | X | ||||
| Clinical opioid dependence ICD-10 diagnosis retrieved from medical records | X | ||||
| Prescribed opioid dose retrieved from medical records | X | ||||
| Duration of opioid therapy | X | ||||
| TLFB-interview (self-reported patterns of opioid use) | X | X | |||
| MINI (J)-interview substance use disorders according to DSM-5 | X | X | |||
| Physical functional tests | |||||
| Mini-BESTest (balance) | X | ||||
| 10 m walk test (walking speed) | X | ||||
| Blood sample | X | ||||
| Research-specific PROMs | X | X | |||
| Extraction of registry data | X | X |
*The research visit has to be scheduled no more than 6 weeks before or after the clinical consultation and completion of the online PROMs.
†Interviews are conducted by telephone during follow-up.
ICD-10, International Classification of Diseases, 10th Revision; MINI, Mini-International Neuropsychiatric Interview; PROMs, patient-reported outcome measures; TLFB, time-line follow-back.