Sample size calculation
| Sample size and precision estimates for primary endpoints based on previous studies | ||||
| Incidence | Sample size | Precision | 95% CI | |
| hs-TnI | 28% | 310 | 5% | 23% to 33% |
| NT-proBNP | 22% | 264 | 5% | 17% to 27% |
| NT-proBNP | 22% | 310 | 4.61% | 17.4% to 26.6% |
hs-TnI, high-sensitivity cardiac troponin; NT-proBNP, N-terminal pro-brain natriuretic peptide.