Punjab, India | Indonesia | Myanmar | Nasarawa, Nigeria | Vietnam | |
Year of programme initiation | 2016* | 2017 | 2017 | 2015 | 2017 |
Time period of data included | February 2016–June 2021 | January 2017–February 2022 | June 2017–March 2018 | July 2017–December 2020 | June 2017–December 2018 |
Data retrieval date | June 2021 | March 2022 | March 2020 | January 2021 | January 2019 |
Scope of data collected | Initial patients treated and longer term scale-up | Initial patients treated and longer-term scale-up | Initial patients treated only | Initial patients treated only | Initial patients treated only |
Data source | Custom web-based system | Excel and custom web-based system | Electronic case-based medical record system (OpenMRS) | Paper records at facilities | Paper records at facilities |
Geographic coverage of data collected | 1 state | 17 provinces | 3 states and regions | 1 state | 7 provinces |
N and type of health facilities/sites included | 59—hospitals, HIV treatment centres, opioid substitution therapy centres and prisons | 38—national referral hospitals, provincial hospitals and district hospitals, prison hospitals, military hospitals, police hospitals and one private hospital | 8—general hospitals, specialist hospitals | 2—outpatient and internal medicine departments from a general hospital and a specialist hospital | 8—two national hospitals, five provincial hospitals and one district health centre |
N patients included | 93 460 | 7424 | 2065 | 139 | 1869 |
% of all data covered during time period on public sector DAA initiations | 100 | 100 | 100 | 8.1 | 100 |
Programme approach to case-finding | General adult population, PLHIV, PWID, prisoners, patients from private sector tested positive | Patients at internal medicine/liver wards, PLHIV at treatment centres, PWIDs, prisoners, haemodialysis patients | Patients at medical wards, PLHIV, PWIDs, men who have sex with men, female sex workers, multi-transfused recipients, HCW, haemodialysis patients, patients from private sector or blood donors tested positive and eligible for public sector care | General adult population (provider-initiated testing and counselling), PLHIV, PWID | PLHIV, PWID, HCW, patients at liver wards; 2019 campaign targeting general population in one province |
Patient screening, diagnosis and treatment fee structure | Free of charge | Free of charge if patients have national insurance. Non-insured patients pay for consumables and services | Free of charge (PPP patients pay for VL and treatment at subsidised prices) | Out of pocket | Out of pocket or insurance co-pay (DCV free of charge) |
Definition of cirrhosis during time period of data included | APRI >2 and FIB-4 >3.25 in adults. Decompensated cirrhosis defined using clinical criteria (or clinician’s judgement) and the Child-Pugh staging system. | APRI>1. Patients at the national hospital were staged using Fibroscan >11.7. Data on decompensated cirrhosis not available. | Initially APRI of >2; changed to >1.5 in the National Simplified Treatment Guidelines for HCV published in 2019. Decompensated cirrhosis defined using clinical criteria (or clinician’s judgement) and the Child-Pugh staging system. | APRI >2. Data on decompensated cirrhosis not available. | APRI >2 or a Fibroscan >12.5 kPa; patients at provincial and district level facilities were staged using APRI while patients at the national hospital were staged using Fibroscan. Decompensated cirrhosis defined using clinical criteria (or clinician’s judgement) and the Child-Pugh staging system. |
Definition of treatment completion | Picking up the prescription for the final month of treatment | Picking up the prescription for the final month of treatment | Coming for a visit post-treatment completion | Picking up the prescription for the final month of treatment | Patients who did not return for SVR12 testing were called by health facility staff to confirm whether treatment was completed |
*The programme was officially launched in June 2016, but a small number of patients initiated in the months prior.
.APRI, AST to platelet ratio index; DCV, daclatasvir; HCV, hepatitis C virus; HCW, healthcare worker; PLHIV, people living with HIV; PPP, public private partnership; PWID, people who inject drugs; SVR12, sustained virologic response at 12 weeks; VL, viral load.