Classification accuracy of the M6NP and M4 at the 2.5%, 5% and 10% threshold
| Threshold | Accuracy measure | M6NP | M4 | P value |
| 2.5% | Sensitivity | 97 (94 to 99) | 91 (88 to 95) | <0.01 |
| False positive rate | 61 (58 to 65) | 43 (40 to 46) | <0.01 | |
| Negative predictive value | 98 (96 to 99) | 96 (94 to 97) | <0.01 | |
| Percentage classified as low risk | 31 (28 to 34) | 46 (44 to 50) | <0.01 | |
| 5% (used in previous studies) | Sensitivity | 95 (92 to 98) | 85 (81 to 90) | <0.01 |
| False positive rate | 50 (47 to 54) | 37 (34 to 40) | <0.01 | |
| Negative predictive value | 97 (96 to 99) | 94 (92 to 96) | <0.01 | |
| Percentage classified as low risk | 40 (37 to 42) | 52 (50 to 55) | <0.01 | |
| 10% | Sensitivity | 91 (87 to 94) | 80 (75 to 85) | <0.01 |
| False positive rate | 39 (36 to 43) | 30 (37 to 34) | <0.01 | |
| Negative predictive value | 96 (94 to 98) | 92 (90 to 94) | <0.01 | |
| Percentage classified as low risk | 49 (46 to 52) | 58 (56 to 61) | <0.01 |
Reported as percentage (95% CI).