Maternal systolic and mean arterial blood pressure
| Systolic blood pressure | Mean arterial blood pressure | |||||
| Akrinor n=440 | Phenylephrine n=412 | P value | Akrinor n=440 | Phenylephrine n=412 | P value | |
| t0 (mm Hg) | 137.7±17.2 | 136.6±17.7 | 0.268 | 99.2±13.3 | 99.6±13.9 | 0.695 |
| t1 (mm Hg) | 117.0±19.4 | 121.8±19.9 | <0.001 | 82.3±14.9 | 86.4±15.7 | <0.001 |
| 0%–10% decline | 159 (36.7) | 209 (52.0) | <0.001 | 146 (33.9) | 189 (47.0) | <0.001 |
| 10%–20% decline | 133 (30.7) | 115 (28.6) | 0.505 | 121 (28.1) | 103 (25.6) | 0.425 |
| 20%–30% decline | 84 (19.4) | 45 (11.2) | 0.001 | 89 (20.6) | 63 (15.7) | 0.063 |
| <100 mm Hg | 66 (15.1) | 49 (12.0) | 0.185 | |||
| <60 mm Hg | 20 (4.6) | 19 (4.6) | 1.00 | |||
| ≥20% decline | 145 (33.5) | 79 (19.7) | <0.001 | 166 (38.5) | 113 (28.1) | 0.001 |
| t2 (mm Hg) | 118.4±18.1 | 123.0±18.6 | <0.001 | 83.1±13.7 | 86.9±14.9 | <0.001 |
| 0%–10% decline | 172 (39.6) | 211 (52.8) | <0.001 | 143 (33.1) | 172 (43.1) | 0.003 |
| 10%–20% decline | 144 (33.2) | 112 (28.0) | 0.105 | 131 (30.3) | 125 (31.3) | 0.754 |
| 20%–30% decline | 76 (17.5) | 53 (13.3) | 0.089 | 100 (23.1) | 65 (16.3) | 0.013 |
| <100 mm Hg | 44 (10.0) | 33 (8.1) | 0.323 | |||
| <60 mm Hg | 10 (2.3) | 12 (2.9) | 0.667 | |||
| ≥20% decline | 119 (27.4) | 77 (19.3) | 0.005 | 162 (37.5) | 103 (25.8) | <0.001 |
| t3 (mm Hg) | 121.7±12.1 | 119.5±12.8 | 0.014 | 84.1±9.8 | 82.9±10.6 | 0.058 |
| 0%–10% decline | 190 (43.7) | 167 (41.4) | 0.513 | 131 (30.2) | 105 (26.1) | 0.185 |
| 10%–20% decline | 164 (37.7) | 153 (38.0) | 0.937 | 168 (38.7) | 151 (37.5) | 0.712 |
| 20%–30% decline | 76 (17.5) | 71 (17.6) | 0.956 | 113 (26.0) | 106 (26.3) | 0.930 |
| <100 mm Hg | 6 (1.4) | 18 (4.4) | 0.008 | |||
| <60 mm Hg | 0 (0) | 1 (0.2) | 0.484 | |||
| ≥20% decline | 82 (18.9) | 84 (20.8) | 0.470 | 141 (32.5) | 149 (37.0) | 0.173 |
| t4 (mm Hg) | 125.7±16.0 | 116.9±17.2 | <0.001 | 89.8±13.1 | 84.4±13.3 | <0.001 |
| 0%–10% decline | 232 (53.3) | 144 (35.7) | <0.001 | 217 (50.0) | 138 (34.2) | <0.001 |
| 10%–20% decline | 135 (31.0) | 139 (34.5) | 0.287 | 134 (30.9) | 129 (32.0) | 0.724 |
| 20%–30% decline | 56 (12.9) | 91 (22.6) | <0.001 | 61 (14.1) | 88 (21.8) | 0.003 |
| <100 mm Hg | 13 (3.0) | 54 (13.1) | <0.001 | |||
| <60 mm Hg | 5 (1.1) | 10 (2.4) | 0.195 | |||
| ≥20% decline | 69 (15.9) | 122 (30.3) | <0.001 | 85 (19.6) | 139 (34.5) | <0.001 |
| tmin (mm Hg) | 100.6±13.1 | 105.0±14.5 | <0.001 | 70.2±10.7 | 73.2±11.8 | <0.001 |
| 0%–10% decline | 25 (5.7) | 44 (10.9) | 0.007 | 28 (6.5) | 31 (7.7) | 0.489 |
| 10%–20% decline | 101 (23.2) | 140 (34.7) | <0.001 | 78 (18.0) | 94 (23.3) | 0.058 |
| 20%–30% decline | 147 (33.8) | 122 (30.3) | 0.275 | 128 (29.6) | 133 (33.0) | 0.283 |
| <100 mm Hg | 205 (46.7) | 133 (32.4) | <0.001 | |||
| <60 mm Hg | 64 (14.6) | 45 (10.9) | 0.124 | |||
| ≥20% decline | 312 (71.7) | 222 (55.1) | <0.001 | 333 (76.9) | 281 (69.7) | 0.019 |
t0=baseline, first measurement in the OR; t1=5 min after spinal anaesthesia; t2=10 min after SPA; t3=last measurement in the OR; t4=first measurement on the IMC; tmin=lowest SBP. Mean±SD, n (%), n=number of cases, p value test on difference between AK and P.
AK, Akrinor; IMC, Intermidate Care; P, phenylephrine; SBP, systolic blood pressure; SPA, spinal anaesthesia.