g/L | (2.5% to 97.5%) | P value | |
Baseline concentration | 99.29 | (98.06 to100.52) | <0.001 |
Age in years | 2.74 | (2.50 to 2.97) | <0.001 |
Female (ref: male) | 1.23 | (0.61 to 1.85) | <0.001 |
HBB/malaria status | |||
HbAA/− (ref) | -- | ||
HbAS/− | −1.87 | (−2.80 to –0.94) | <0.001 |
HbAC/− | −1.15 | (−3.89 to 1.58) | 0.41 |
HbSC/− | −12.35 | (–15.90 to –8.80) | <0.001 |
HbSS/− | −28.92 | (–33.31 to –24.52) | <0.001 |
HbAA/+ | −12.93 | (–13.76 to –12.10) | <0.001 |
HbAS/+ | −10.76 | (–12.02 to –9.49) | <0.001 |
HbAC/+ | −9.42 | (–12.65 to –6.20) | <0.001 |
HbSC/+ | −27.85 | (–35.65 to –20.06) | <0.001 |
HbSS/+ | −37.25 | (–43.56 to –30.94) | <0.001 |
Rural (ref: urban) | −0.03 | (−0.87, 0.81) | 0.94 |
Wealth | |||
Richer/richest (ref) | -- | ||
Middle | −0.15 | (−1.05 to 0.76) | 0.75 |
Poorer | −1.89 | (−3.04 to –0.74) | <0.01 |
Poorest | −3.80 | (−5.10 to –2.50) | <0.001 |
Mother’s education | |||
None or primary (ref) | -- | ||
Secondary or higher | 1.12 | (0.28 to1.97) | <0.01 |
Multivariate linear regression results to predict adjusted haemoglobin concentration. The baseline haemoglobin concentration is in the first row, with the following rows summarising the effect of risk factors.
HbAA, normal HBB; HbAC, haemoglobin C trait; HbAS, sickle cell trait; HbSC, heterozygous for HbS and HbC; HbSS, sickle cell anemia.