Univariate and multivariate Cox proportional hazard analysis of AF recurrence during a follow-up of 12 months after cryoablation according to sex
| Cohort | Baseline characteristics | Univariate | Multivariate | ||
| Hazard ratio (95% CI) | P value | Adjusted hazard ratio (95% CI) | P value | ||
| Women (N=210) | Age | 0.99 (0.96 to 1.02) | 0.545* | 0.98 (0.95 to 1.01) | 0.193 |
| Diabetes mellitus | 2.84 (1.40 to 5.78) | 0.004† | 3.13 (1.50 to 6.55) | 0.002 | |
| Heart failure | 2.73 (1.07 to 6.95) | 0.035† | 2.84 (1.10 to 7.33) | 0.031 | |
| Men (N=440) | Age | 1.00 (0.98 to 1.02) | 0.847* | 1.00 (0.98 to 1.02) | 0.999 |
| Type of AF (persistent) | 1.71 (1.10 to 2.67) | 0.018† | 1.71 (1.10 to 2.68) | 0.018 | |
| Chronic kidney disease (eGFR <60 mL/min/1.73 m2) | 2.21 (1.11 to 4.40) | 0.024† | |||
| LVEF | 0.96 (0.93 to 0.99) | 0.008† |
*Demographic variables tested further with multivariable analysis.
†Significant univariable baseline characteristic (α ≤ 0.10) tested further with multivariable analysis.
AF, atrial fibrillation; eGFR, Estimated Glomerular Filtration Rate ; LVEF, left ventricular ejection fraction.