Factors explaining sex differences observed in HRQoL following MI
| Parameter | EQ-5D model, coefficient (95% CI) | EQ VAS model, coefficient (95% CI) |
| Sex effect | −0.07 (−0.08 to −0.06) | −3.78 (−4.65 to −2.91) |
| Adding age, BMI, IMD | −0.06 (−0.07 to −0.05) | −3.33 (−4.20 to −2.40) |
| Adding pharmacotherapy and coronary intervention | −0.06 (−0.08 to −0.05) | −3.27 (−4.16 to −2.27) |
| Adding final diagnosis | −0.06 (−0.08 to −0.05) | −3.17 (−4.06 to −2.27) |
| Adding comorbidities and risk factors* | −0.07 (−0.08 to −0.06) | −3.77 (−4.64 to −2.90) |
| Adding baseline value of the HRQoL metric† | −0.06 (−0.07 to −0.05) | −2.56 (−3.38 to −1.73) |
*Baseline EQ-5D for EQ-5D model and baseline EQ VAS for EQ VAS model.
†Previous MI, age, previous coronary artery bypass graft surgery, smoking status, previous percutaneous coronary intervention, family history of coronary heart disease, peripheral vascular disease, hypercholesterolemia, previous angina, chronic obstructive pulmonary disease or asthma, diabetes mellitus, chronic renal failure, hypertension, cerebrovascular disease and heart failure.
BMI, body mass index; EQ-5D, EuroQol five dimension; EQ VAS, EuroQol visual analogue scale; HRQoL, health-related quality of life; IMD, index of multiple deprivation; MI, myocardial infarction.