Table 3

Flow chart over plasma sampling for pharmacokinetic analysis from a peripheral vein during study part A and B

Sample noSampling time
Study part AStudy part B
Pre 1Pre-infusionPre-infusion
Post 1Directly after end of infusion, t=0 minDirectly after end of infusion, t=0 min
Post 2t=5 mint=150 min (2.5 hours)
Post 3t=15 min
Post 4t=30 min
Post 5t=60 min (1 hour)
Post 6t=120 min (2 hours)
Post 7t=360 min (6 hours)
Post 8t=before the patient is discharged from the hospital