Table 1

Secondary endpoints

EndpointDefinitionTimeline
Intraoperative
 Blood lossMillilitresDay of the surgery
 Operative timeMinutesDay of the surgery
 Surgical approachOpen/minimal invasiveDay of the surgery
 Spleen preservationYes/noDay of the surgery
Postoperative endpoints
 CR-POPFAccording to ISGPF definition15Within 90 days after surgery
 DGEAccording to ISGPF definition20Within 90 days after surgery
 PPHAccording to ISGPF definition21Within 90 days after surgery
 QoL questionnairesPAN-26, EORTC-30 (PAN-26/ EORTC-C30: European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire -Core Questionnaire (C30) - Pancreatic Cancer Module)22Until 12 months after surgery
 Readmission rateAny readmission in the hospitalWithin 90 days after surgery
 Reoperation rateAny surgery after index surgeryWithin 90 days after surgery
 Overall survivalTime from surgery to last follow-upWithin 12 months after surgery
  • CR-POPF, clinically relevant postoperative pancreatic fistula; DGE, delayed gastric emptying; ISGPF, Internation Study Group Pancreatic Fistula; ISGPF, International Study Group of Pancreatic Fistula; PPH, postpancreatectomy haemorrhage; QoL, quality of life.