Endpoint | Definition | Timeline |
Intraoperative | ||
Blood loss | Millilitres | Day of the surgery |
Operative time | Minutes | Day of the surgery |
Surgical approach | Open/minimal invasive | Day of the surgery |
Spleen preservation | Yes/no | Day of the surgery |
Postoperative endpoints | ||
CR-POPF | According to ISGPF definition15 | Within 90 days after surgery |
DGE | According to ISGPF definition20 | Within 90 days after surgery |
PPH | According to ISGPF definition21 | Within 90 days after surgery |
QoL questionnaires | PAN-26, EORTC-30 (PAN-26/ EORTC-C30: European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire -Core Questionnaire (C30) - Pancreatic Cancer Module)22 | Until 12 months after surgery |
Readmission rate | Any readmission in the hospital | Within 90 days after surgery |
Reoperation rate | Any surgery after index surgery | Within 90 days after surgery |
Overall survival | Time from surgery to last follow-up | Within 12 months after surgery |
CR-POPF, clinically relevant postoperative pancreatic fistula; DGE, delayed gastric emptying; ISGPF, Internation Study Group Pancreatic Fistula; ISGPF, International Study Group of Pancreatic Fistula; PPH, postpancreatectomy haemorrhage; QoL, quality of life.