Table 3

Outcome variables

Outcome	Variable	Definition
Mental disorder diagnosis* (5 years before to 1 year after index date)	Mood or anxiety disorder	At least one hospitalisation with a diagnosis of depressive disorder, affective psychoses, neurotic depression, adjustment reaction or bipolar disorder; or at least one hospitalisation with a diagnosis for an anxiety state, phobic disorder or obsessive compulsive disorder; or two or more physician visits with a diagnosis of depressive disorder, affective psychoses, adjustment reaction or anxiety disorders.
	Psychotic disorder	At least one hospitalisation with a diagnosis of a psychotic disorder; or at least one physician visit with a diagnosis of a psychotic disorder.
	Personality disorder	At least one hospitalisation with a diagnosis for a personality disorder; or at least one physician visit with a diagnosis for a personality disorder.
	Substance use disorder	Comorbid substance use disorders other than a disorder for (or as a result of) methamphetamine use: at least one hospitalisation with a diagnosis for alcohol or drug-induced psychosis, alcohol or drug dependence or non-dependent abuse of drugs; or at least one physician visit with a diagnosis for alcohol or drug-induced psychosis, alcohol or drug dependence or non-dependent abuse of drugs.
Other health services use (5 years before to 1 year after index date)	Winnipeg Fire Paramedic Service (WFPS) contact	Any engagement with WFPS, regardless of documented methamphetamine use.
	Methamphetamine-related ED visits	Emergency department visit (in Winnipeg) where methamphetamine use was documented.
	Methamphetamine-related hospitalisations	Hospitalisation (in Winnipeg) where methamphetamine use was documented.
	Any hospitalisations	Any hospitalisation (in Winnipeg).
	Methamphetamine-related physician visits	Physician visit (in Winnipeg) where methamphetamine use was documented.
	Any physician visits	Any physician visit (in Winnipeg).
ED outcomes after olanzapine administration	Use of chemical or physical restraints	Documentation of chemical or physical restraint use in the WFPS data.
	Patient left the ED	From ED data, determine whether patient: Left against medical advice. Left prior to discharge. Elopement (left treatment space without discussion with provider). Left without being seen.
	Length of ED stay	From ED data, determine time until seen by a physician, time until treatment, length of treatment time.
	Triage classification	From ED data: CTAS.

*See appendix 3 for diagnosis codes.
CTAS, Canadian Triage Acuity Scale; ED, emergency department.