Subgroup analyses for the association between herpes zoster exposure and Sjogren syndrome risk based on age, sex and CCI (exclude CTD)
| OR (95% CI) | P value* | |
| Age group | 0.270 | |
| ＜50 years | 2.09 (1.67 to 2.61) | |
| ≥50 years | 1.84 (1.65 to 2.05) | |
| Sex | 0.146 | |
| Female | 1.94 (1.75 to 2.15) | |
| Male | 1.50 (1.11 to 2.04) | |
| CCI group (exclude CTD) | 0.001 | |
| 0 | 2.13 (1.88 to 2.43) | |
| ≥1 | 1.63 (1.32 to 2.02) |
Comorbidity was identified within 1 year before the index date.
*P for interaction.
CCI, Charlson Comorbidity Index; CTD, connective tissue disease.