Cost-effectiveness results with sensitivity analysis for key model uncertainties
| Base case impact | Base case+higher CS cost | Base case+higher CS cost and ESMK programme cost | Pessimistic impact | Pessimistic impact+higher CS cost | Pessimistic impact+higher CS cost and ESMK programme cost | |
| Input parameters | ||||||
| Population rate of emergency CS | 15% | 15% | 15% | 10% | 10% | 10% |
| Emergency CS gap attributable to anaesthesia | 30% | 30% | 30% | 10% | 10% | 10% |
| Incremental CS procedure cost* | US$183 | US$366 | US$366 | US$183 | US$366 | US$366 |
| Programme cost multiplier | 1 x | 1 x | 2 x | 1 x | 1 x | 2 x |
| Outcomes | ||||||
| Undiscounted programme cost | US$1.18 m | US$1.18 m | US$2.36 m | US$1.18 m | US$1.18 m | US$2.36 m |
| Undiscounted total cost | US$6.43 m | US$11.68 m | US$12.85 m | US$1.65 m | US$2.12 m | US$3.30 m |
| Additional emergency CS | 28 704 | 28 704 | 28 704 | 2580 | 2580 | 2580 |
| Maternal lives saved | 316 | 316 | 316 | 28 | 28 | 28 |
| Fetal lives saved | 4736 | 4736 | 4736 | 426 | 426 | 426 |
| Incremental cost-effectiveness ratio | ||||||
| Cost per LY (discounted) | US$44 | US$79 | US$87 | US$125 | US$161 | US$251 |
| Percent of GDPpc per LY (discounted) | 2.8% | 5.1% | 5.6% | 8.0% | 10.3% | 16.1% |
| Cost per maternal LY (discounted) | US$779 | US$1412 | US$1557 | US$2246 | US$2880 | US$4492 |
| Percent of GDPpc per maternal LY (discounted) | 50% | 91% | 100% | 144% | 185% | 288% |
*Excess cost of caesarean delivery cost above the cost of normal vaginal delivery.
CS, caesarean delivery procedure; ESMK, Every Second Matters-Ketamine; GDPpc, per capita gross domestic product; LY, life-year.