Post hoc per-protocol analysis: 6 months follow-up of intervention patients who attended 50% or more pulmonary rehabilitation sessions compared with usual care
| Intervention n=13 | Usual care n=26 | |||
| Mean (SD) | Mean change (SD) (95% CI) | Mean (SD) | Mean change (SD) (95% CI) | |
| SGRQ—Total* | 44.9 (24.3) | −16.6 (14.5) (−25.3 to 7.8) | 40.8 (20.0) | −8.1 (20.8) (−16.5 to 0.3) |
| SGRQ—Impacts | 36.6 (22.7) | −14.1 (16.8) (−24.3 to -4.0) | 30.1 (20.0) | −7.5 (25.5) (−17.7 to 2.9) |
| SGRQ—Activity | 53.3 (33.7) | −22.9 (21.3) (−35.8 to -10.1) | 49.2 (24.8) | −10.5 (23.3) (−19.9 to -1.1) |
| SGRQ—Symptoms | 54.7 (24.8) | −12.6 (20.1) (−24.7 to -0.4) | 57.7 (24.8) | −6.0 (22.4) (15.1 to 3.1) |
| MRC Dyspnoea Score | 2.6 (1.0) | −1.0 (0.8) | 2.8 (0.9) | −0.3 (0.8) |
| CAT† | 16.2 (7.1) | −5.5 (4.8) | 17.7 (7.6) | −2.7 (6.5) |
| PHQ-9 Depression Score‡ | 4.8 (5.0) | −0.9 (3.4) | 3.8 (3.0) | −1.9 (3.2) |
| GAD-7 Anxiety Score‡ | 2.8 (3.6) | −0.8 (3.2) | 2.0 (2.1) | −1.3 (2.6) |
| Stanford Self-Efficacy Score | 7.3 (1.7) | 1.6 (2.0) | 7.3 (1.2) | 0.7 (1.5) |
| ISWT§ | 217.5 (85.7) | 17.5 (72.6) | 216 (99.4) | −29.2 (74.1) |
| Self-reported number of exacerbations in the last 6 months | 2.9 (1.5) | 0.1 (1.5) | 3.2 (1.27) | 0.9 (1.7) |
| Total Physical Activity Scores, MET-minutes/week | 1078.5 (1498.5) | 72.92 (1816.8) | 1857.0 (2853.4) | −1170.7 (2753.3) |
*Minimal clinically important difference (MCID) 4 points.
†MCID −2 points.
‡MCID 20% reduction.
§MCID 35–36 m
CAT, COPD Assessment Test; COPD, chronic obstructive pulmonary disease; GAD-7, Generalised Anxiety Disorder-7; ISWT, incremental shuttle walk test; MET, metabolic equivalent of task; PHQ-9, Patient Health Questionnaire-9; SGRQ, St George’s Respiratory Questionnaire.