Effect of pulmonary rehabilitation at 8 weeks and 6 months for patients in the intervention and usual care groups
| 8 weeks follow-up | 6 months follow-up | |||||||
| Intervention | Usual care | Intervention | Usual care | |||||
| Mean (SD) n=13 | Mean change (SD) (95% CI) | Mean (SD) n=25 | Mean change (SD) (95% CI) | Mean (SD) n=27 | Mean change from baseline (SD) (95% CI) | Mean (SD) n=26 | Mean change from baseline (SD) (95% CI) | |
| SGRQ—Total* | 32.3 (27.4) | −24.9 (25.4) (−40.3 to - 9.6) | 48.0 (20.8) | −0.5 (18.0) (−8.1 to 7.0) | 48.1 (23.5) | −4.4 (19.8) (−12.3 to 3.4) | 40.8 (20.0) | −8.1 (20.8) (−16.5 to 0.3) |
| SGRQ—Impacts | 23.3 (25.6) | −22.7 (22.6) (−36.4 to - 9.1) | 37.6 (23.2) | 0.3 (22.9) (−9.2 to 9.7) | 38.4 (23.6) | −2.4 (21.0) (−10.7 to 5.9) | 30.1 (20.0) | −7.5 (25.5) (−17.7 to 2.9) |
| SGRQ—Activity | 42.5 (32.9) | −30.5 (29.4) (−48.3 to - 12.8) | 58.6 (20.3) | 1.1 (17.7) (−6.2 to 8.5) | 58.5 (29.8) | −7.8 (26.5) (−18.3 to 2.7) | 49.2 (24.8) | −10.5 (23.3) (−19.9 to - 1.1) |
| SGRQ—Symptoms | 41.0 (31.6) | −21.6 (37.3) (−44.1 to 1.0) | 60.5 (25.7) | −4.2 (21.4) (−13.2 to 4.9) | 58.1 (23.4) | −4.5 (24.1) (−14.1 to 5.0) | 57.7 (24.8) | −6.1 (22.4) (−15.1 to 3.1) |
| MRC Dyspnoea Score | 2.5 (1.2) | −0.9 (1.3) | 3.0 (0.6) | −0.2 (0.6) | 2.9 (1.0) | −0.4 (1.0) | 2.8 (0.9) | −0.3 (0.8) |
| COPD Assessment Test (CAT) Score† | 13.8 (8.5) | −6.6 (7.4) | 18.3 (7.0) | −1.4 (5.0) | 17.9 (8.5) | −1.7 (7.3) | 17.7 (7.6) | −2.7 (6.5) |
| PHQ-9 Depression Score‡ | 2.8 (1.9) | −2.8 (2.9) | 5.5 (5.1) | −0.3 (3.9) | 4.74 (4.2) | −1.2 (3.8) | 3.8 (3.0) | −1.9 (3.2) |
| GAD-7 Anxiety Score‡ | 1.9 (1.6) | −0.9 (3.0) | 3.3 (3.5) | −0.3 (2.8) | 2.51 (3.3) | −0.7 (2.8) | 2.0 (2.1) | −1.3 (2.6) |
| Stanford Self-Efficacy Score | 7.8 (1.2) | 1.9 (1.5) | 6.9 (1.5) | 0.3 (1.8) | 7.0 (1.5) | 1.2 (2.1) | 7.3 (1.2) | 0.7 (1.5) |
| ISWT§ | 316.2 (134.3) | 120.8 (89.5) | 247.6 (113.5) | −13.2 (110.7) | 217.6 (89.6) | −7.1 (92.5) | 216 (99.4) | −29.2 (74.1) |
| Number of exacerbations in the last 6 months | 3.5 (1.1) | 0.7 (1.3) | 3.6 (1.0) | 1.3 (1.7) | 3.2 (1.3) | 0.5 (2.5) | 3.2 (1.3) | 0.92 (1.7) |
| Total Physical Activity Scores. MET-minutes/week (SD) | 783.2 (1509.9) | −1309.6 (2539.0) | 1634.7 (1532.0) | −1393.1 (2838.3) | 943.6 (1163.5) | −1653.3 (4650.6) | 1857.0 (2853.4) | −2386.7 (5537.9) |
*A reduction in SGRQ is a positive patient outcome, minimal clinically important difference (MCID) 4 points.
†MCID: −2 points.
‡MCID 20% reduction.
§MCID 35–36 m
COPD, chronic obstructive pulmonary disease; GAD-7, Generalised Anxiety Disorder-7; ISWT, incremental shuttle walk test; MET, metabolic equivalent of task; PHQ-9, Patient Health Questionnaire-9; SGRQ, St George’s Respiratory Questionnaire.