Table 2

Cox proportional hazards model of the WCC trajectory, baseline WCC quartile and type 2 diabetes onset

New-cases/total (n)Incidence density (%)Model 1Model 2Model 3
WCC trajectory
 Trajectory 148/21812.2111
 Trajectory 296/36642.621.19 (0.84–1.69)*1.26 (0.89–1.79)*1.2 (0.84–1.71)*
 Trajectory 380/16614.822.1 (1.47–3.01)2.14 (1.49–3.08)1.94 (1.32–2.83)
 Trajectory 425/3387.43.42 (2.11–5.55)3.64 (2.22–5.97)3.08 (1.82–5.21)
Baseline WCC (quartile)
 Q1 (<5.4)44/20832.11111
 Q2 (5.4–6.4)58/20802.791.32 (0.89–1.96)*1.26 (0.85–1.87)*1.16 (0.78–1.73)*
 Q3 (6.40–7.5)64/18013.551.69 (1.15–2.48)1.56 (1.06–2.29)1.43 (0.96–2.13)*
 Q4 (>7.5)83/19604.232.02 (1.4–2.91)2.04 (1.41–2.96)1.68 (1.13–2.5)
  • Model 1: Unadjusted.

  • Model 2: adjusted for age, sex.

  • Model 3: adjusted for model 2 plus total protein, aspartate aminotransferase level, alanine aminotransferase level, γ-glutamyl transpeptidase level, total bilirubin level, direct bilirubin level, red cell count and platelet count.

  • *p>0.05, baseline WCC (quartile): Quartile grouping of WCC at the first physical examination.

  • WCC, white cell count.