Multivariate analysis of medical workers’ knowledge that low-dose spiral CT can effectively screen early-stage lung cancer
| Characteristic | OR (95% CI) | P value | |
| Sex | 0.8731 (0.7214 to 1.0566) | 0.1632 | |
| Nation (after merging all non-Chinese Han) | 1.5131 (0.9583 to 2.3889) | 0.0755 | |
| Education level (after merging Doctor of Philosophy and master, undergraduate and college) | Doctor of Philosophy and master (X3) | 1.2687 (0.7919 to 2.0326) | 0.3224 |
| Undergraduate and college (X2) | 1.0314 (0.7228 to 1.4719) | 0.8646 | |
| Professional title (after merging senior and associate, primary and none) | Senior and associate (X3) | 1.2917 (0.9417 to 1.7717) | 0.1125 |
| Middle (X2) | 0.9109 (0.7639 to 1.0863) | 0.2989 | |
| Post | Public administration (X4) | 1.0046 (0.6993 to 1.4432) | 0.9802 |
| Technician (X3) | 0.6976 (0.5399 to 0.9015) | 0.0059 | |
| Nurse (X2) | 0.6970 (0.5718 to 0.8496) | 0.0004 | |
| Department | Others (X6) | 0.8402 (0.6458 to 1.0930) | 0.1944 |
| Thoracic surgery (X5) | 0.6971 (0.4975 to 0.9766) | 0.0360 | |
| General practice (X4) | 0.9008 (0.6562 to 1.2367) | 0.5182 | |
| Health management centre (X3) | 1.3107 (0.9330 to 1.8413) | 0.1188 | |
| Respiratory medicine (X2) | 0.9113 (0.6837 to 1.2146) | 0.5263 | |
| Years working for medicine and health | ≥15 (X4) | 1.1032 (0.8611 to 1.4134) | 0.4373 |
| 10~14 (X3) | 1.2267 (0.9840 to 1.5291) | 0.0693 | |
| 5~9 (X2) | 1.1800 (0.9807 to 1.4196) | 0.0795 | |
| How much do you know about the dangers of lung cancer? | Very familiar (X5) | 1.3409 (0.4655 to 3.8626) | 0.5868 |
| Quite familiar (X4) | 1.1971 (0.4253 to 3.3697) | 0.7333 | |
| Generally familiar (X3) | 1.0375 (0.3708 to 2.9024) | 0.9441 | |
| Unfamiliar (X2) | 0.9024 (0.3207 to 2.5396) | 0.8458 | |
| How much do you know about lung cancer diagnosis? | Very familiar (X5) | 2.3582 (0.9183 to 6.0562) | 0.0746 |
| Quite familiar (X4) | 1.3055 (0.5572 to 3.0589) | 0.5394 | |
| Generally familiar (X3) | 1.4262 (0.6244 to 3.2577) | 0.3996 | |
| Unfamiliar (X2) | 1.2301 (0.5533 to 2.7346) | 0.6114 | |
| How much do you know about lung cancer screening guidelines? | Very familiar (X5) | 0.6333 (0.2793 to 1.4356) | 0.2739 |
| Quite familiar (X4) | 1.3560 (0.6891 to 2.6685) | 0.3779 | |
| Generally familiar (X3) | 1.0796 (0.5659 to 2.0596) | 0.8161 | |
| Unfamiliar (X2) | 1.2374 (0.6647 to 2.3035) | 0.5018 | |
| Which lung cancer screening method will you select according to high-risk population? | Unclear (X7) | 1.4965 (0.4669 to 4.7966) | 0.4975 |
| Chest-enhanced CT (X6) | 0.6414 (0.2217 to 1.8557) | 0.4125 | |
| General CT (X5) | 1.0210 (0.8474 to 1.2302) | 0.8267 | |
| Low-dose spiral CT (X4) | 1.2507 (1.0268 to 1.5234) | 0.0263 | |
| Thin-slice CT (X3) | 0.3725 (0.1036 to 1.3393) | 0.1304 | |
| MRI (X2) | 1.1325 (0.1317 to 9.7382) | 0.9098 | |
| Which lung cancer screening method do you think is the most effective according to high-risk population? | Unclear (X7) | 1.1893 (0.7353 to 1.9237) | 0.4798 |
| Chest X-ray (X6) | 1.0225 (0.7713 to 1.3554) | 0.8773 | |
| Sputum cell culture (X5) | 1.1913 (0.9060 to 1.5664) | 0.2100 | |
| General CT (X4) | 1.4058 (1.1069 to 1.7854) | 0.0052 | |
| Biopsy (X3) | 0.3064 (0.0567 to 1.6557) | 0.1694 | |
| Low-dose spiral CT (X2) | 3.7530 (3.0027 to 4.6906) | <0.0001 | |
| Do you know the effect of treatment for early-stage lung cancer? | Very familiar (X5) | 2.7148 (1.2411 to 5.9384) | 0.0124 |
| Quite familiar (X4) | 1.5008 (0.7744 to 2.9085) | 0.2291 | |
| Generally familiar (X3) | 1.2534 (0.6651 to 2.3621) | 0.4848 | |
| Unfamiliar (X2) | 1.1946 (0.6475 to 2.2039) | 0.5693 | |
| How much do you know about low-dose spiral CT screening for lung cancer? | Very familiar (X5) | 4.0945 (2.2668 to 7.3962) | <0.0001 |
| Quite familiar (X4) | 2.1904 (1.4654 to 3.2741) | 0.0001 | |
| Generally familiar (X3) | 2.3933 (1.6869 to 3.3956) | <0.0001 | |
| Unfamiliar (X2) | 1.3480 (0.9710 to 1.8714) | 0.0744 | |
| Does your medical institution provide low-dose spiral CT screening? | Unclear (X3) | 0.4882 (0.4057 to 0.5874) | <0.0001 |
| Yes (X2) | 3.2567 (2.5867 to 4.1002) | <0.0001 | |
| Do you know the limitation and potential risk of low-dose spiral CT screening for lung cancer? | Unclear (X3) | 1.1348 (0.7977 to 1.6144) | 0.4820 |
| Yes (X2) | 1.7385 (1.4011 to 2.1573) | <0.0001 | |
| Do you know how to follow up the patients with lung nodules who have been detected by low-dose spiral CT screening? | 1.8258 (1.5000 to 2.2223) | <0.0001 | |
| Which is the main reason you recommend low-dose spiral CT screening? | Low-dose spiral CT screening for lung cancer is cost-effective (X4) | 0.4009 (0.2914 to 0.5515) | <0.0001 |
| Refer to the Chinese Lung Cancer Screening Guidelines (X3) | 0.7195 (0.6015 to 0.8606) | 0.0003 | |
| Low-dose spiral CT screening can reduce lung cancer mortality (X2) | 0.5904 (0.4774 to 0.7301) | <0.0001 | |
| What is the main reason why you do not recommend low-dose spiral CT screening? | No necessity for screening (X4) | 0.8297 (0.6689 to 1.0292) | 0.0894 |
| High proportion of false-positive results (X3) | 0.7710 (0.6429 to 0.9246) | 0.0050 | |
| Exposure to radiation (X2) | 1.3080 (1.0776 to 1.5875) | 0.0066 | |
| What is the most important factor affecting low-dose spiral CT screening? | The technical level of medical technicians (X6) | 0.7723 (0.6324 to 0.9050) | 0.0116 |
| The level of awareness for medical workers (X5) | 0.6514 (0.4842 to 0.9214) | 0.0178 | |
| Whether there is health insurance (X4) | 0.8687 (0.7272 to 1.2500) | 0.3365 | |
| The level of awareness for residents (X3) | 0.8947 (0.6051 to 1.1450) | 0.3436 | |
| Income (X2) | 0.8324 (0.6187 to 1.1500) | 0.1981 | |
| Where will you recommend the screened patients for treatment who had pulmonic nodules? | West China hospital (X5) | 3.6246 (2.0612 to 6.3736) | <0.0001 |
| Provincial hospital (X4) | 3.1476 (1.7910 to 5.5317) | <0.0001 | |
| Municipal hospital (X3) | 3.5942 (2.0644 to 6.2578) | <0.0001 | |
| County-level hospital (X2) | 2.0295 (1.1339 to 3.6325) | 0.0172 |