Variables | Total (N=7924) | Trajectory 1 (N=2181) | Trajectory 2 (N=3664) | Trajectory 3 (N=1741) | Trajectory 4 (N=338) | P value |
Age | 40 (34–54) | 45 (36–56) | 40 (34–52) | 39 (34–52) | 38 (34–48.25) | <0.01 |
Sex | <0.01 | |||||
Men | 2849 | 579 | 1362 | 723 | 185 | |
Women | 5075 | 1602 | 2302 | 1018 | 153 | |
Total protein (g/L) | 70.4 (67.7–73.3) | 69.8 (67.2–72.8) | 70.6 (67.8–73.2) | 70.7 (68.1–73.8) | 70.6 (68.1–73.9) | <0.01 |
Albumin (g/L) | 46.1 (44.3–47.8) | 46 (44.3–47.6) | 46.1 (44.3–47.9) | 46.1 (44.2–47.9) | 46.1 (44.3–48) | 0.22 |
Albumin to globulin ratio | 1.89 (1.7–2.11) | 1.92 (1.73–2.14) | 1.9 (1.71–2.11) | 1.86 (1.66–2.06) | 1.86 (1.69–2.07) | <0.01 |
Aspartate aminotransferase (U/L) | 24 (20–28) | 23 (20–27) | 23 (20–27) | 24 (20–28) | 24 (21–30) | <0.01 |
Alanine aminotransferase (U/L) | 24 (19–32) | 22 (18–29) | 24 (19–32) | 26 (19–36) | 29 (21–42.25) | <0.01 |
γ-glutamate transpeptidas (U/L) | 18 (13–29) | 16 (12–23.5) | 18 (13–29) | 21 (14–34.5) | 27 (17–45.25) | <0.01 |
Total bilirubin (umol/L) | 12.6 (9.9–16) | 12.9 (10.3–16.3) | 12.7 (10.1–16) | 12.2 (9.4–15.75) | 11.9 (9.1–15.03) | <0.01 |
Direct bilirubin (umol/L) | 4 (2.9–5.2) | 4.1 (3–5.2) | 4 (3–5.2) | 3.8 (2.8–5.1) | 3.8 (2.6–4.9) | <0.01 |
Total bile acid (umol/L) | 2.33 (1.35–3.98) | 2.33 (1.34–3.89) | 2.3 (1.38–3.97) | 2.41 (1.3–4.12) | 2.25 (1.45–3.89) | 0.69 |
White cell count ×109/L | 6.4 (5.4–7.5) | 5 (4.4–5.5) | 6.4 (5.8–7) | 7.9 (7.3–8.7) | 9.9 (9.1–11) | <0.01 |
Red cell count ×109/L | 4.76 (4.47–5.13) | 4.63 (4.36–4.95) | 4.78 (4.48–5.14) | 4.88 (4.58–5.22) | 5.03 (4.68–5.38) | <0.01 |
Platelet count ×109/L | 230 (198–265) | 212 (184–242) | 231 (201–264) | 246 (214–283) | 266 (233.75–304.75) | <0.01 |
WCC, white cell count.