Table 1

Baseline characteristics according to WCC trajectory

VariablesTotal
(N=7924)
Trajectory 1
(N=2181)
Trajectory 2
(N=3664)
Trajectory 3
(N=1741)
Trajectory 4
(N=338)
P value
Age40 (34–54)45 (36–56)40 (34–52)39 (34–52)38 (34–48.25)<0.01
Sex<0.01
 Men28495791362723185
 Women5075160223021018153
Total protein (g/L)70.4 (67.7–73.3)69.8 (67.2–72.8)70.6 (67.8–73.2)70.7 (68.1–73.8)70.6 (68.1–73.9)<0.01
Albumin (g/L)46.1 (44.3–47.8)46 (44.3–47.6)46.1 (44.3–47.9)46.1 (44.2–47.9)46.1 (44.3–48)0.22
Albumin to globulin ratio1.89 (1.7–2.11)1.92 (1.73–2.14)1.9 (1.71–2.11)1.86 (1.66–2.06)1.86 (1.69–2.07)<0.01
Aspartate aminotransferase (U/L)24 (20–28)23 (20–27)23 (20–27)24 (20–28)24 (21–30)<0.01
Alanine aminotransferase (U/L)24 (19–32)22 (18–29)24 (19–32)26 (19–36)29 (21–42.25)<0.01
γ-glutamate transpeptidas (U/L)18 (13–29)16 (12–23.5)18 (13–29)21 (14–34.5)27 (17–45.25)<0.01
Total bilirubin (umol/L)12.6 (9.9–16)12.9 (10.3–16.3)12.7 (10.1–16)12.2 (9.4–15.75)11.9 (9.1–15.03)<0.01
Direct bilirubin (umol/L)4 (2.9–5.2)4.1 (3–5.2)4 (3–5.2)3.8 (2.8–5.1)3.8 (2.6–4.9)<0.01
Total bile acid (umol/L)2.33 (1.35–3.98)2.33 (1.34–3.89)2.3 (1.38–3.97)2.41 (1.3–4.12)2.25 (1.45–3.89)0.69
White cell count ×109/L6.4 (5.4–7.5)5 (4.4–5.5)6.4 (5.8–7)7.9 (7.3–8.7)9.9 (9.1–11)<0.01
Red cell count ×109/L4.76 (4.47–5.13)4.63 (4.36–4.95)4.78 (4.48–5.14)4.88 (4.58–5.22)5.03 (4.68–5.38)<0.01
Platelet count ×109/L230 (198–265)212 (184–242)231 (201–264)246 (214–283)266 (233.75–304.75)<0.01
  • WCC, white cell count.