Table 2

Association between continuity of care (CoC) and probability of being prescribed statins, anticoagulants, antiplatelets or antihypertensives, and adherence to these prescribed medicines

CoCStatins for primary prevention*Statins for secondary prevention†Anticoagulants‡Antiplatelets§Antihypertensives¶
ORP value95% CIORP value95% CIORP value95% CIORP value95% CIORP value95% CI
Being prescribedStatins, N=49 345Statins, N=20 488Anticoagulants, N=8935Antiplatelets, N=15 993Antihypertensives, N=27 929
 Absence of CoC0.73<0.0010.59 to 0.850.770.0800.57 to 1.030.830.3230.57 to 1.200.550.0220.33 to 0.920.51<0.0010.39 to 0.65
 Below average CoC0.900.0440.81 to 1.000.910.2130.77 to 1.060.790.0020.68 to 0.920.910.1920.79 to 1.050.69<0.0010.61 to 0.78
 Average CoC1.000.9720.93 to 1.071.020.6530.92 to 1.140.970.6230.85 to 1.101.000.9530.89 to 1.130.890.0050.83 to 0.97
 Above average CoCRef.Ref.Ref.Ref.Ref.
 Perfect CoC1.230.0361.01 to 1.491.370.0051.10 to 1.711.050.6440.85 to 1.311.370.0091.08 to 1.741.100.0780.99 to 1.23
Adherence toStatins, N=16 273Statins, N=6574Anticoagulants, N=4694Antiplatelets, N=1927Antihypertensives, N=10 982
 Absence of CoC0.940.7930.60 to 1.470.610.1700.31 to 1.230.550.1010.27 to 1.121.710.5770.26 to 11.370.830.4180.53 to 1.30
 Below average CoC0.920.3740.77 to 1.100.850.2870.64 to 1.140.960.7000.77 to 1.191.220.2160.89 to 1.670.880.1530.73 to 1.05
 Average CoC0.940.1890.82 to 1.040.750.0110.60 to 0.940.960.5520.81 to 1.121.070.6360.80 to 1.441.030.7160.87 to 1.23
 Above average CoCRef.Ref.Ref.Ref.Ref.
 Perfect CoC0.930.5860.76 to 1.171.090.6430.77 to 1.540.950.7590.66 to 1.361.120.7060.62 to 2.040.980.9110.74 to 1.31

  • Estimates of OR from multivariable logistic regression models adjusted for age, gender, medicine review last year, Cambridge Comorbidity Score, deprivation, number of general practitioner (GP) consultation in last 2 years and clustering in GP practices.

  • *Patients aged 65+ not diagnosed with CVD-related conditions. Analysis on being prescribed statins N=49 345, and on adherence to prescribed statins N=16 273. Online supplemental tables S1 and S2 show the complete results for the univariable and the multivariable logistic regressions.

  • †Patients aged 30+ diagnosed with heart failure, coronary heart disease, peripheral vascular disease, stroke and transient ischaemic attack, or diabetes (type one or 2). Analysis on being prescribed statins N=20 488, and on adherence to prescribed statins N=6574. Online supplemental tables S3 and S4 show the complete results for the univariable and the multivariable logistic regressions.

  • ‡Patients aged 30+ and diagnosed with atrial fibrillation or venous thromboembolism (pulmonary embolus or deep venous thrombosis recorded within year prior the index date). Analysis on being prescribed anticoagulants N=8935, and on adherence to prescribed anticoagulants N=4694. Online supplemental tables S5 and S6 show the complete results for the univariable and the multivariable logistic regressions.

  • §Patients aged 30+ and diagnosed with heart failure, coronary heart disease, peripheral vascular disease, or stroke & transient ischaemic attack. Analysis on being prescribed antiplatelets N=15 993, and on adherence to prescribed antiplatelets N=1927. Online supplemental tables S7 and S8 show the complete results for the univariable and the multivariable logistic regressions.

  • ¶Patients aged 30+ who were diagnosed with hypertension or had high blood pressure recordings within 1 year before index date. Analysis on being prescribed antihypertensives N=27 929, and on adherence to prescribed antihypertensives N=10 982. Online supplemental tables S9 and S10 show the complete results for the univariable and the multivariable logistic regressions.