Population characteristics by region, low-income and lower-middle-income countries as of December 2021.
| Characteristics | Total | Sub-Saharan Africa | Europe and Central Asia | Latin America and the Caribbean | South Asia | East Asia and the South Pacific | Middle East and North Africa |
| Population (millions) | 3669 | 1092 | 98 | 46 | 1876 | 303 | 253 |
| % vaccinated | 37.4 | 7.3 | 32.6 | 40.9 | 54.3 | 50.7 | 27.3 |
| % fully vaccinated | 24.3 | 3.7 | 22.9 | 32.0 | 34.2 | 39.5 | 20.9 |
| No. reported COVID-19 deaths (thousands) | 945 | 54 | 110 | 35 | 566 | 103 | 77 |
| No. estimated Excess Deaths from COVID-19 (95% CI) (thousands) | 9309 (2612 to 13 782) | 1393 (0 to 2240) | 272 (22 to 313) | 154 (89 to 185) | 6495 (1787 to 9554) | 438 (231 to 700) | 556 (317 to 791) |